
Guesthouse vacation rentals in Isabela
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Isabela
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Isabela guesthouse rentals
Family-friendly guest house rentals

Guesthouse in Aguadilla
4.95 out of 5 average rating, 66 reviewsHilda’s Guest, Central Location With Easy Access

Guesthouse in BO BARRERO
4.69 out of 5 average rating, 469 reviewsHiddenStudio Oceanview,Private Beach Access Rincon

Private room in Isabela
4.55 out of 5 average rating, 155 reviewsJuanky's Place 1

Guesthouse in Aguada
4.63 out of 5 average rating, 133 reviewsVillaMarsana Guesthouse of Wellness BigSuite w/2BR

Guesthouse in Hatillo
4.68 out of 5 average rating, 44 reviewsCGH Jardin del Mar, Hatillo
Guest house rentals with a patio

Guesthouse in Camuy
4.96 out of 5 average rating, 45 reviewsHacienda Colinas De Anaisa

Guesthouse in Aguada
5 out of 5 average rating, 4 reviewsHeaven's Doors Rock Castle - Villa for 6 Guests

Guesthouse in Aguadilla Pueblo
4.9 out of 5 average rating, 10 reviewsOcean view Cliff House

Guesthouse in Aguacate
5 out of 5 average rating, 15 reviewsHacienda Del Mar-New APRT Ocean Views&Latin Vibes

Guesthouse in Aguadilla
5 out of 5 average rating, 9 reviewsGazebo Suite-central, clean, quiet-no cleaning fee

Guesthouse in Rincón
5 out of 5 average rating, 10 reviewsIn the Clouds VelBela

Guesthouse in Aguacate
4.86 out of 5 average rating, 22 reviewsCasa Mango
Guest house rentals with a washer and dryer

Guesthouse in Rincon
4.98 out of 5 average rating, 44 reviewsCasa Loba Luxe Apartment w/pool, views and tub

Guesthouse in Ponce
4.92 out of 5 average rating, 108 reviewsThe*Cottage, Adorable 1-BR,with romantic patio.

Guesthouse in Ciales
4.9 out of 5 average rating, 10 reviewsChalet de la Hacienda

Guesthouse in Hatillo
4.77 out of 5 average rating, 70 reviewsVilla Melolai- cozy and tropical

Guesthouse in Arecibo
5 out of 5 average rating, 399 reviewsExperience Tropical Camping at a Cabin Close to the Ocean

Guesthouse in Jayuya
4.98 out of 5 average rating, 157 reviewsPradera Country House

Guesthouse in Aguadilla Pueblo
5 out of 5 average rating, 14 reviewsBreeze Villa 1

Guesthouse in Rincon
4.81 out of 5 average rating, 120 reviewsCozy Casita #1 at Sandy Beach - 1bdrm w/Ocean View
Destinations to explore
- Guesthouse rentals West Indies
- House rentals West Indies
- Guesthouse rentals Puerto Rico
- House rentals Puerto Rico
- House rentals San Juan
- Guesthouse rentals San Juan
- House rentals Isabela
- Kid-friendly rentals Isabela
- Apartment rentals Isabela
- Monthly Rentals Isabela
- Private suite rentals Isabela
- Rentals with a washer and dryer Isabela
- Beachfront rentals Isabela
- Smoking-friendly rentals Isabela
- Fitness-friendly rentals Isabela
- Villa rentals Isabela
- Rentals with a fire pit Isabela
- Beach house rentals Isabela
- Tiny house rentals Isabela
- Rentals with beach access Isabela
- Rentals with pools Isabela
- Family-friendly rentals Isabela
- Condo rentals Isabela
- Rentals with outdoor seating Isabela
- Waterfront rentals Isabela
- Pet-friendly rentals Isabela
- Rentals with an EV charger Isabela
- Rentals with a hot tub Isabela
- Rentals with a patio Isabela
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes