Vacation rentals in Guthrie County

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Top-rated vacation rentals in Guthrie County

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite

The front exterior of the house features a broad staircase leading to a glass-paneled door framed by two large pillars. Multiple windows are visible, allowing natural light to enter, while a well-kept yard surrounds the entrance, contributing to the inviting facade.

Home in Guthrie Center

Small Town Mansion

Step into the charm of this beautiful early-1900s Sears & Roebuck home—truly a one-of-a-kind getaway. Located in the heart of Guthrie Center, you’ll be just 15 miles north of I-80 and 8 miles west of Lake Panorama. Enjoy peaceful mornings on the front porch or stretch out and relax in the spacious living room. A large and thoughtfully curated book collection awaits any reading enthusiast. The entire home is yours to settle into, unwind and make your own! Ample parking-double car garage & street.

FamilyLocationAmenities

4.92 out of 5 average rating, 182 reviews

Top guest favorite

A modern cabin is situated on a raised deck, surrounded by bare trees. Large windows allow for ample natural light, with warm sunset tones reflecting off the glass. The structure's clean lines and contrasting colors create a contemporary aesthetic within a forested setting.

Cabin in Stuart

Cabin w/ Hot Tub + Fire Pit + Private Trails

Looking for a place to slow down, reconnect, and make memories? Located 30 minutes from WDM and 90 minutes of Omaha, this modern cabin on a private wooded property is designed for couples, families, and small groups. Guests love: • Hot tub under the stars • Views from every room • Outdoor fire pit and fireplace • Fully stocked kitchen • River access and nature trails • Peaceful setting with easy access to small-town attractions Experience the ultimate retreat and choose your own adventure.

ValueLocationCheckout

4.94 out of 5 average rating, 118 reviews

Top guest favorite

Cabin in Panora

Beautiful Pine Log Cabin at Lake Panorama

Discover the warmth and character of this beautiful Amish built pine log home, perfectly nested in a wooded area at Lake Panorama. Offering 2 bedrooms and 2 bathrooms, this home blends rustic charm with modern updates, from soaring vaulted ceilings to an open-concept living/dining area. Outdoor living shines with a large spruce deck, patio with pergola, and included teak table and chairs - perfect for entertaining or relaxing. ***Because of open stairways no guests under 8 will be allowed.

LocationFamilySleep quality

5.0 out of 5 average rating, 10 reviews

Superhost

Home in Panora

Luxe Modern Waterfront Lakehouse

Experience the perfect blend of comfort, and natural beauty at this home. Situated on a waterfront lot with its own sandy beach, this home offers unmatched serenity and direct lake access. Enjoy expansive lake views from nearly every room, relax on the patio, or golf Lake Panorama’s National Golf Course a premier destination for golf lovers. Whether you’re here for a peaceful getaway, a family gathering, or a golf retreat, this home offers the perfect backdrop for unforgettable memories.

LocationFamilyAmenities

5.0 out of 5 average rating, 4 reviews

Top guest favorite

Home in Panora

Peaceful Stay 3.63 Acres 2 Minutes to Lake & Golf

Escape to this peaceful Panora, IA retreat set on 3.63 acres of private yard. The bright, open-concept main level brings the living, dining and fully equipped kitchen together. The home has three bedrooms, two full baths and one half bath, plus a garage for convenience. Step outside to the back porch to watch amazing sunsets while grilling dinner, or go out on the lawn during the summer where yard games provide outdoor fun. Families are provided with kids’ toys, games, and a pack ’n play.

FamilyValueIndoor spaces

5.0 out of 5 average rating, 29 reviews

Top guest favorite

A cabin features a sloped roof and is surrounded by trees and open grassland. A deck extends from the front, leading to an entrance. The landscape includes several green trees, adding a natural feel to the peaceful setting.

Place to stay in Guthrie Center

Seely Creek Cabin Getaway and Hunting Lodge

Seely Creek Cabin is a romantic getaway, a fabulous hunting destination, and a relaxing weekend spot! The cabin is nestled on 40 acres - 20 being wooded and another 20 open including a fully stocked pond and a walking trail! This beautifully unique property comes equipped with a fully stocked kitchen including all cooking necessities (except for food), a smart tv, wifi, games and cards in the entertainment center, as well as 3 comfy queen sized beds with all linens you would need!

FamilyLocationAmenities

4.97 out of 5 average rating, 104 reviews

Top guest favorite

A view from the outdoor patio showcases a manicured lawn bordered by trees, leading towards a serene lake. A red gravel path intersects the scene. A grill and a seating area are present on the patio, while an American flag gently waves in the breeze.

Home in Panora

Fire Creek Homes

Our condo at Lake Panorama National Golf Course is a quiet retreat for the entire family or golf buddies. Located on the fairway of Hole #5 with a view of the lake. 3 bedrooms and 3 bathrooms with laundry on site makes this a comfortable experience in our 1,900 SF condo. Need more space? Check out our additional rental, just a few units away: https://www.airbnb.com/rooms/1622458927125168285?unique_share_id=93de812c-23a0-42c0-8eca-0a3e754349f7&viralityEntryPoint=1&s=76

LocationFamilyBeach

4.92 out of 5 average rating, 26 reviews

Top guest favorite

Shipping container in Stuart

Cozy Country Container Stay w/ Hot Tub & Fire Pit!

Cozy 1-bed shipping container home in rural Stuart, IA. Perfect for couples or solo travelers. •Sleeps 2 • Queen bed • Full kitchen & Bath •Hot tub • Fire pit • Grill •Shared pond for fishing & scenic views. •Friendly horses & dogs on site (winter months will vary) (guests can interact) please treat them with kindness. •Peaceful country setting- perfect for relaxing & stargazing •You may see a critter or two-true country living!

LocationFamilyIndoor spaces

4.99 out of 5 average rating, 80 reviews

Top guest favorite

The rustic exterior of a cottage is showcased, with a wood-paneled facade and a front porch featuring two white chairs. Large windows allow natural light to enter, while an air conditioning unit is seen on the side. Lush greenery surrounds the property, illuminated by soft sunlight.

Cabin in Coon Rapids

The Rookery Cottage - Access scenic hiking trails

This rustic cottage is a quiet retreat in the heart of the Middle Raccoon River Valley. Situated on a private acreage within Whiterock Conservancy, guests can easily access 40mi+ of scenic hiking and mountain biking trails, float the nearby river, or enjoy dark sky viewing. A "rookery" is a nesting site for herons, a bird that prefers quiet, undisturbed habitat near water. And so the Rookery Cottage seeks to provide a natural escape from the daily grind.

LocationValueNearby

4.98 out of 5 average rating, 340 reviews

Guest favorite

A spacious dining area features a large wooden table surrounded by matching chairs. Warm wood paneling and flooring create a welcoming atmosphere. Adjacent to the dining space, a well-equipped kitchen can be seen, highlighted by stainless steel appliances and soft lighting.

Home in Adair

Warm, cozy 4 bedroom lodge-style country home

Located in the country just 8 miles north of I-80 Exit 76 between Des Moines and Omaha, this lodge-style, 4 bedroom, 2 1/2 bath home is the perfect place for a quiet weekend getaway. The home is perfectly decorated with a rustic, mountain cabin-y feel, with lots of seating for dining or playing games together, or relaxing on couches and chairs in the living room. There is a large patio outside to enjoy grilling or your cup of coffee in the sunshine.

LocationFamilyCheck-in

4.86 out of 5 average rating, 35 reviews

Top guest favorite

A light-filled kitchen features open shelving adorned with colorful glassware and decorative items. A modern refrigerator and pink microwave complement the white cabinetry. A central island with bar stools offers seating, while a floral arrangement adds a touch of charm.

Apartment in Stuart

The 1894 by Doe A Deer | 2 br, 1 bath apartment

Welcome to The 1894 by Doe A Deer - a newly renovated 2 bedroom spacious apartment located in historic downtown Stuart! Enjoy restaurants, boutiques and coffee just steps from the front door. Relax and enjoy the view from your new favorite small town spot. Perfect for getting ready with your wedding party, families, girls trips, anniversaries & more! We can’t wait to host you!

LocationFamilyParking

4.97 out of 5 average rating, 196 reviews

Guest favorite

A modern kitchen area features black cabinetry and sleek stainless steel appliances. A large island with a white countertop is complemented by four black bar stools. A potted plant adds a touch of greenery, while a wall clock is mounted above the counter for convenience.

Apartment in Casey

Brick Street Loft

Welcome to Brick Street Loft! A newly renovated, open concept upper level 2 bedroom apartment in Historic downtown Casey. During your visit, you can experience local coffee, food and shopping. Relax and enjoy the view of the historic brick street. We have the perfect space for getting bridal parties, families, girls trips & more!

LocationFamilyKitchen

4.96 out of 5 average rating, 26 reviews