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Vacation rentals in Florence County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Florence County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Apartment in Lake City
Home away from Home #5 - Stay Smart-Save
Located on Main Street in a family home that has been updated to be like brand new. 5 has one bedroom with door, a private entrance, bath and dressing area, micro- kitchen, living & dining combination. An optional lockout bedroom(R7) with private entrance can be added, making this a 2 bed, 2 bath apt. Amenities include 2 CABLE & ROKU TVs, wifi, front door parking, Fresh brewed In Room Coffee. Uptown is a one mile walk along Main Street. 1/2 way from New York to Miami. Hablamos Espanol.
$54 per night
Cottage in Timmonsville
*Cottage Near Florence and I-95*
Located just 5 mins from I-95 (exit 153) and 12 minutes from Florence, this quaint cottage sits on 6 acres with private deck, firepit & large back yard in a peaceful, country location. Your pets are welcome (max of 2, please). We offer king bed in master, 3 wall-mounted TV's (two 55” & one 32”), coffee bar with Keurig, strong WiFi. We also use 100% cotton sheets and quilts for your maximum sleeping comfort. Lock Box on front door for self-check-in! Come stay with us. 🙂
$101 per night
Guesthouse in Florence
The Poolside Cottage: Close to Interstates
New floors and paint in January of 2023. Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, queen sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.
$102 per night
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