Vacation rentals in Florence County

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Top-rated vacation rentals in Florence County

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Superhost

Apartment in Lake City

Home away from Home #5 - Stay Smart-Save

Located on Main Street in a family home that has been updated to be like brand new. 5 has one bedroom with door, a private entrance, bath and dressing area, micro- kitchen, living & dining combination. An optional lockout bedroom(R7) with private entrance can be added, making this a 2 bed, 2 bath apt. Amenities include 2 CABLE & ROKU TVs, wifi, front door parking, Fresh brewed In Room Coffee. Uptown is a one mile walk along Main Street. 1/2 way from New York to Miami. Hablamos Espanol.

$54 per night

Superhost

Cottage in Timmonsville

*Cottage Near Florence and I-95*

Located just 5 mins from I-95 (exit 153) and 12 minutes from Florence, this quaint cottage sits on 6 acres with private deck, firepit & large back yard in a peaceful, country location. Your pets are welcome (max of 2, please). We offer king bed in master, 3 wall-mounted TV's (two 55” & one 32”), coffee bar with Keurig, strong WiFi. We also use 100% cotton sheets and quilts for your maximum sleeping comfort. Lock Box on front door for self-check-in! Come stay with us. 🙂

$101 per night

Superhost

Guesthouse in Florence

The Poolside Cottage: Close to Interstates

New floors and paint in January of 2023. Palm Trees, colorful flowers, hammocks and quiet space await in this tropic-like oasis just minutes from I-95/20. Hundreds of reviews acknowledge this idyllic setting. We are a Florence Airbnb favorite for travelers. We offer a queen bed, full bathroom, queen sleeper sofa, strong wifi and TV. We even provide breakfast bars and coffee to help you jump start your day as you set off for the next journey. We look forward to hosting you.

$102 per night

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Superhost

Guest suite in Florence

Private Apartment 5 Min Away From I-95 & I-20

Please come and enjoy our Guest Apartment in Florence, SC! A great stop for travelers to rest during their trips. Guests will have a private entrance to the apartment that is attached but separate from the main house, where me and my family live. Guest privacy will always be respected. One bedroom has a queen size bed, a second bedroom has a daybed. The bathroom has a tub and shower. The kitchen has a stove/oven. The apartment is cleaned and sanitized after each guest leaves. Thank you!

$75 per night

Superhost

Apartment in Florence

Kuker Carriage House-Sleeps 3-Downtown/Near I95&20

Kuker Carriage House was originally a barn that has been converted into apartments in the heart of the newly revitalized Florence downtown. This first floor unit was just fully renovated and is ready for you to enjoy, whether for a short overnight stop or a longer extended stay. This space is bright and open with lots of natural light and a fully enclosed private courtyard. Queen bed, twin daybed, full bath, Wifi and TV. Walkable to parks and restaurants. Just 4 miles from I95 and I20

$96 per night

Superhost

Home in Effingham

Clean and Comfortable 3B/2B Home w/ 2-Car Garage

Peaceful and centrally located. 3 BR, 2 bath fully furnished house with 2 car garage in an established neighborhood. Great for healthcare and business professionals. MUSC Florence and McLeod Health are located within 9 miles from the property. Conveniently located between Charleston, SC and Myrtle Beach, SC and close to I-95 and I-20. A discount will be given at checkout for weekly and monthly rentals. Wifi, cable, and utilities included. Pack 'n play/high chair available upon request.

$90 per night

Superhost

Loft in Marion

The Loft at 109

located at 109 Arch Street in downtown Marion, South Carolina, is a fully furnished apartment that offers all the amenities of home -and more. Housed in a historic building in the heart of the Pee Dee, The Loft has charming character with exposed brick walls and original hardwood floors. Offered as a nightly rental, your experience begins as you're greeted with gas lanterns and continues inside where you'll find our 1,000 square foot living space On site massage therapist (appointment required)

$211 per night

Superhost

Farm stay in Hemingway

Quiet farmhouse near the beach

The best memories are made on the farm. Life is just better away from the hustle and bustle of city lights and busy schedules. Come stay in this recently renovated fourth generation 1950s farmhouse on an 80 acre working farm. Unwind on the porch, walk trails, find millions of years old sharks teeth, build a bonfire, pick blackberries, swim in the ponds, collect walnuts, or just relax while you’re here but don’t forget to wish on a dandelion or a shooting star before you leave.

$101 per night

Superhost

Cottage in Darlington

Darlington Farm House Near I-95 & Florence

Nicknamed the "Little House," this charming old farm house has been family owned since the early 1800s. The house is located on 3 acres of land with a small pond. Fully renovated interior includes a kitchen with new appliances. Convenient location less than 10 minutes from I-95. Experience country living at its finest, perfect to break up a long drive, visit relatives, or just get some good old peace and quiet.

$84 per night

Superhost

Cottage in Florence

DOWNTOWN Pine Cottage

DOWNTOWN FLORENCE!! Walk to town and Enjoy the local shopping and dining!! Cottage is located within the walls of a private and gated residence. You will have privacy and security during your stay. House is fully furnished with everything you would need for a lovely visit. Wifi , tv, coffee maker, microwave, hot plate, toaster oven are a few of the amenities this house offers. Outside, there is a sitting area, playhouse, grilling area and a fire pit. Come and Enjoy this 1912 property!!

$68 per night

Superhost

Cottage in Effingham

Granada

Quiet retreat just 10 minutes from the city of Florence. Perfect stay for a quiet getaway, a short drive to the beach for the day, or convenient for a weekend event . Enjoy amazing sunsets , an ocasional deer, birds and other wildlife from your front or back porch in the privacy of your secluded retreat . Whether you decide to stay in and grill out, visit downtown Florence for a meal, or go for a walk around the property and visit the pond, you will be close to nature and enjoy privacy

$165 per night

Superhost

Home in Florence

Cozy home in Florence, SC

Relax with the whole family at this peaceful place to stay, located in Florence, South Carolina. Places nearby: Francis Marion University - 5 mins Florence Regional Airport - 8 mins Florence County Museum and Timrod Park - 10 mins Jeffree Creeks Park - 13 mins Florence Veterans Park - 20 mins Marion County Museum - 25 mins Darlington Raceway - 30 mins

$105 per night

Superhost

Home in Florence

Pineapple House Historic Southern Charm Downtown

Welcome to the Pineapple House! Experience southern hospitality in this historic charmer perfect for professionals. -Quaint, quiet downtown neighborhood walkable to restaurants -Fast wifi, laundry room, large fenced backyard w/ fire pit, off-street parking -Fully loaded kitchen, 2 Roku TV's, queen sleeper sofa, relaxing front porch -3 min to FMU Performing Arts Center, 5 min to McLeod Hospital, 10 min to FMU & MUSC Medical Center. -Perfect for short or long stays!

$80 per night

Superhost

Home in Florence

Bright, Airy, and Convenient Home on King

This fully furnished home is perfect for those traveling to work in Florence. Whether you are a traveling healthcare professional, in town for a short term assignment, or desire to work in one of our many industry settings this home is for you. Located in a quiet established neighborhood in central Florence, you can enjoy a cozy restful evening at home. You will be close to hospitals (McLeod and MUSC Flo), major hwys (I-95/I-20), and great local restaurants. Welcome to your home away from home!

$90 per night

Superhost

Home in Florence

Cozy 3 Bedroom Home! Located NEAR MUSC-Florence

Forget your worries in this spacious and serene space. Cozy home located in a quiet subdivision in Florence, SC. This elegant fully furnished home has three bedrooms, two queen size beds, one king size bed, walk in closet in every room, two full bathrooms, dryer in private laundry room, full kitchen, and a smart TV. Perfect family friendly home away from home.

$140 per night

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Vacation rentals in Florence County

Top-rated vacation rentals in Florence County

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