
Guesthouse vacation rentals in Central Florida
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Central Florida
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Central Florida guesthouse rentals
Family-friendly guest house rentals

Guesthouse in Trenton
4.88 out of 5 average rating, 163 reviewsSprings capital of the world

Guesthouse in Port Orange
4.87 out of 5 average rating, 198 reviewsChic & Cozy Modern Pool Home

Guesthouse in Tampa
4.85 out of 5 average rating, 331 reviewsHyde Park Tree House, Tampa, FL - Great location

Guesthouse in Windermere
4.94 out of 5 average rating, 258 reviewsParadise nook near Orlando's theme parks

Guesthouse in Fort McCoy
4.88 out of 5 average rating, 275 reviewsBlueberry Farm Country Cottage

Guesthouse in Vero Beach
4.92 out of 5 average rating, 151 reviewsCountry Life Guest house with pool

Guesthouse in Hobe Sound
4.8 out of 5 average rating, 152 reviewsSandee's Cottage

Guesthouse in Port Orange
4.93 out of 5 average rating, 331 reviewsRelaxing Tropical Pool Get Away Suite
Guest house rentals with a patio

Guesthouse in Sebastian
4.92 out of 5 average rating, 127 reviewsQuiet cottage on Sebastian River property

Guesthouse in Tampa
4.88 out of 5 average rating, 134 reviewsLuxury guesthouse, 1 mile from Hard Rock Casino

Guesthouse in Tampa
4.97 out of 5 average rating, 115 reviewsCute Guesthouse by the Riverwalk, w/patio and WFH

Guesthouse in Tampa
4.99 out of 5 average rating, 135 reviewsQuiet and clean guest house!

Guesthouse in Tampa
4.96 out of 5 average rating, 261 reviewsTiny House Oasis Blue Vatican . Near MacDill Base

Guesthouse in Sarasota
4.89 out of 5 average rating, 101 reviewsCity Garden Cottage

Guesthouse in Tarpon Springs
4.83 out of 5 average rating, 52 reviewsCasa Pina. Cute 1bed 1 bath with patio and king

Guesthouse in Tampa
4.85 out of 5 average rating, 172 reviewsAdorable 1 Bedroom Ybor Casita with outdoor patio
Guest house rentals with a washer and dryer

Guesthouse in Lakeland
4.95 out of 5 average rating, 104 reviewsHidden Ruby-Apartment with Kitchen and Laundry

Guesthouse in Dunedin
4.95 out of 5 average rating, 165 reviewsTiki Hut Cottage

Guesthouse in Riverview
4.82 out of 5 average rating, 117 reviewsThe Casita-Adorable guest house!

Guesthouse in Orlando
4.94 out of 5 average rating, 244 reviewsModern Guest Studio (Private) Pool / Spa available

Guesthouse in Brandon
4.88 out of 5 average rating, 56 reviewsAdorable Guesthouse

Guesthouse in St. Petersburg
4.98 out of 5 average rating, 102 reviews2 bedroom guesthouse in hip Grand Central District

Guesthouse in Lady Lake
5 out of 5 average rating, 117 reviewsCute & Cozy Tiny Guesthouse

Guesthouse in St. Petersburg
4.86 out of 5 average rating, 140 reviewsPrivate & Spacious Loft Guest House
Destinations to explore
- Four Corners Vacation rentals
- Kissimmee Vacation rentals
- Tampa Vacation rentals
- Orlando Vacation rentals
- Tampa Bay Vacation rentals
- St Petersburg Vacation rentals
- Saint Johns River Vacation rentals
- Fort Lauderdale Vacation rentals
- Gold Coast Vacation rentals
- Miami Vacation rentals
- Miami Beach Vacation rentals
- Florida Keys Vacation rentals
- Guesthouse rentals United States
- House rentals United States
- House rentals Florida
- Guesthouse rentals Florida
- Bed and breakfasts Central Florida
- Rentals with outdoor seating Central Florida
- Beach condo rentals Central Florida
- Lakehouse rentals Central Florida
- Rentals with a fireplace Central Florida
- Rentals with an accessible height toilet Central Florida
- Bungalow rentals Central Florida
- Monthly Rentals Central Florida
- Smoking-friendly rentals Central Florida
- Rentals with pools Central Florida
- Rentals with breakfast Central Florida
- Ski-in/ski-out rentals Central Florida
- Rentals with a washer and dryer Central Florida
- Rentals with a fire pit Central Florida
- Rentals with a hot tub Central Florida
- Apartment rentals Central Florida
- Loft rentals Central Florida
- Aparthotel rentals Central Florida
- Rentals with a patio Central Florida
- House rentals Central Florida
- Houseboat rentals Central Florida
- Kid-friendly rentals Central Florida
- Townhouse rentals Central Florida
- Serviced apartment rentals Central Florida
- Hotel rentals Central Florida
- Rentals with a kayak Central Florida
- Villa rentals Central Florida
- RV rentals Central Florida
- Resort rentals Central Florida
- Boutique hotel rentals Central Florida
- Cottage rentals Central Florida
- Fitness-friendly rentals Central Florida
- Luxury rentals Central Florida
- Campsite rentals Central Florida
- Family-friendly rentals Central Florida
- Rentals with a home theater Central Florida
- Rentals with an EV charger Central Florida
- Vacation home rentals Central Florida
- Pet-friendly rentals Central Florida
- Rentals with an accessible height bed Central Florida
- Rentals with beach access Central Florida
- Beachfront rentals Central Florida
- Cabin rentals Central Florida
- Waterfront rentals Central Florida
- Condo rentals Central Florida
- Rentals with a sauna Central Florida
- Tiny house rentals Central Florida
- Farmstay rentals Central Florida
- Rentals with lake access Central Florida
- Barn rentals Central Florida
- Private suite rentals Central Florida
- House rentals Orlando
- Guesthouse rentals Orlando
- Guesthouse rentals Saint Johns River
- House rentals Saint Johns River
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Things to do United States
- Sports activities United States
- Wellness United States
- Food and drink United States
- Entertainment United States
- Art and culture United States
- Sightseeing United States
- Nature and outdoors United States
- Things to do Florida
- Sports activities Florida
- Wellness Florida
- Food and drink Florida
- Entertainment Florida
- Sightseeing Florida
- Art and culture Florida
- Nature and outdoors Florida
- Things to do Central Florida
- Sports activities Central Florida
- Food and drink Central Florida
- Art and culture Central Florida
- Nature and outdoors Central Florida
- Sightseeing Central Florida
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes