
Places to stay near Biosphere 2
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Top-rated vacation rentals near Biosphere 2
Guests agree: these stays are highly rated for location, cleanliness, and more.

The Zendo Oasis. Your Private Resort in Tucson.
Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Songbirds N Serenity- Heated Pool & Fall Packages
Add a Celebration Package- champagne, desserts, and more to make your stay extra special. Inquire for pricing. Indulge in a private desert retreat with a heated pool, hot tub, and BBQ. Picture basking in the warm sun, surrounded by the soothing ambiance of your exclusive sanctuary. Be serenaded by songbirds, enjoy Catalina Mountain views, and create lasting memories with loved ones. Escape, revitalize, and make joyous memories in this secluded desert haven. Your perfect getaway awaits!al

West-side Trailhead Retreat in the Sonoran Desert
2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

A Secluded Retreat in Nature - La Casita
La Casita is nestled on 2.3 secluded acres next to the Coronado National Forest. The comfortable vintage cottage has good light and sweeping views of the foothills and woodlands around it. A beautiful garden and various outdoor sitting areas provide relaxing places to enjoy the quiet nature and many birds that live there. The Oracle Ridge trailhead to Mt. Lemmon is just a 5-minute walk from the house. These features and more are what make your stay at La Casita so enjoyable and special.

Cozy Mountain Retreat w/ Hot Tub
Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Charming Private Guesthouse with Mountain View
Check out our weekly and monthly discounts! Enjoy the beautiful mountain view from the cozy wrap around porch. Perfect for your morning coffee. Private guest house located on small horse ranch. Close to hiking, biking, and site seeing. Cozy up to the fire pit in the evening to watch the eastern mountains turn pink as the sun sets in the west. Check out our 120 plus 5 star reviews. This is truly a magical place. Non smoking of any kind, no pets, service animals, infants or children.

Forest Hermitage With Creek. Close To Everything!
Imagine waking up to the sounds of birds chirping and the trickling of water from the creek as you sip your favorite hot drink from the balcony among the pine and fir trees. This cabin is just a stone's throw away from town center with a food shop right across the street, but is a true mountain hermitage where you can unplug and unwind from all your concerns. And with fast Wifi, you can do your best work remotely amidst the serenity of nature while a fresh mountain breeze blows.

Modern Loft w/ Pool & Hot Tub-Views!
Stargaze, admire the incredible mountain views & wildlife at this 2 story gated loft! Enjoy the pool table, above ground pool, hot tub, new appliances/bathroom, grill, Smart TVs, and games! Only minutes away from Tucson's popular hiking trails, 8 mins from Agua Caliente Park, 12 mins from Saguaro National Park, 15 mins from Sabino Canyon, 55 mins from Mount Lemon (a must visit!). The loft has a lot of character and is set up for only 4 guests! No parties, smoking, or gatherings.

Birder AirBnB near the beautiful Catalina mnts
Small quiet casita surrounded by beautiful desert vegetation with a stunning view of the Catalina mountains. Desert wildlife frequently encountered. Near Biosphere II, hiking and biking trails, and a few small-town eateries. Near town of Oro Valley which has restaurants, a movie theater, shopping and events. Six miles N of Catalina State Park and 20 miles SW of Oracle State Park. Birdwatcher friendly with local guide available for birding tours. 1 hr. from airport.

Tucson Poet's Studio
Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Little House in the Desert
Tiny Home. Very private. Peaceful and quiet. Lots of land surrounding. Separate driveway And huge lot area. Dog Ok. NO CATS New, extremely comfortable Queen memory foam/gel mattress in the bedroom and brand new Queen memory foam mattress in the pull out couch. This is the perfect little HOuse in the Desert and brand new! We are available to you and very close in the main house on the other side of the property. The houses are separated by a large brick wall.

Catalina Foothills Azul Courtyard Guest Suite
Welcome to Casita Tolsa! We are close to La Encantada Mall with Shopping, and Restaurants close by. Our Studio Guest Suite has private entrance and parking, private patio. Local Art Galleries close by with views of every mountain range and the city. Enjoy the traditional territorial style, the wood beam ceilings, the patio, the comfy foam mattress/down pillows and comforter. Our place is good for singles, couples, and business travelers.
Popular amenities for vacation rentals near Biosphere 2
Condo rentals with wifi

Upstairs Corner Casita w/ incredible sunset views.

Gorgeous Mountain & City Views, Pools, & Hot Tubs

The Sunrise Suite, a luxury 1 bed condo

Catalina Foothills Getaway

Tasteful, Modern Luxury. Great Location.

Luxury Ventana Canyon Condo!

Saguaro Escape | Pool/Tennis/Hiking/Patio

Ventana Canyon Condo with Pool View
Family-friendly house rentals

Charming U of A Area Cottage

Wild West Hideout - UofA -> 8min

Quiet 2 Bedroom retreat

Cozy Bungalow in The Heart of Tucson 2 bed 1 bath

Nestled in Catalina Mountains with Amazing Views

Serene Vacation Home - Trails, Golf & Dining!

Views-GameRoom-Comfy Beds-Pool-Hiking@Saguaro West

Sonoran Desert hideaway with screen porch
Apartment rentals with air conditioning

Modern Art Loft: Gem Show Haven Wow

Spring Serenity! Chic 1BR Apt – Walk to UofA!

The Saguaro Suite-SW Retreat w/Private Entrance

NO Cleaning FEE Starr Pass Golf Suites- Studio

Jungle Escape • King Bed • Walk Downtown & U of A

Midtown pied-à-terre: Agua Linda Suite

Cottage Guest House,University Area

Charming 1 Bedroom near Downtown
Other great vacation rentals near Biosphere 2

The Outpost

Pet Friendly Casita with striking Mountain View’s

Oasis: Casita Colibrí - Little Hummingbird House

Oracle Retreat

Golden moments in Oro Valley/Tucson

Sorta Summer 'Centro' Rowhouse in Historic Barrio

Luxury Cabin Near Oracle

The Coop- Luxury guest house with ideal location
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