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Places to stay near Biosphere 2

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Top-rated vacation rentals near Biosphere 2

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
Guesthouse in Tucson
4.97 out of 5 average rating, 426 reviews

The Zendo Oasis. Your Private Resort in Tucson.

Discover the Zendo Oasis, your private resort in midtown Tucson. Don't settle for a sterile hotel room that can cost hundreds more. The Zendo offers a retreat atmosphere that will impress. Exercise in our full gym and luxuriate in an infrared or hot stone sauna! After, jump in the pool! Sip wine while enjoying evenings around a chiminea under starlit skies—lounge in the sun or shade on the deck or under louvered patios. The Zendo is close to the UA and downtown. Book now and escape the ordinary!

Top guest favorite
Home in Tucson
4.97 out of 5 average rating, 101 reviews

Songbirds N Serenity- Heated Pool & Fall Packages

Add a Celebration Package- champagne, desserts, and more to make your stay extra special. Inquire for pricing. Indulge in a private desert retreat with a heated pool, hot tub, and BBQ. Picture basking in the warm sun, surrounded by the soothing ambiance of your exclusive sanctuary. Be serenaded by songbirds, enjoy Catalina Mountain views, and create lasting memories with loved ones. Escape, revitalize, and make joyous memories in this secluded desert haven. Your perfect getaway awaits!al

Top guest favorite
The guesthouse is set against a backdrop of desert landscape, showcasing a simple, earthy exterior. A wooden porch with railings invites guests to enjoy the outdoor space. Desert vegetation, including cacti and shrubs, enhances the natural surroundings, along with rocky pathways leading to the house.
Guesthouse in Tucson
4.99 out of 5 average rating, 351 reviews

West-side Trailhead Retreat in the Sonoran Desert

2017 guest house in Tucson Mountain foothills adjacent to Sweetwater Preserve (14+ mi.s of trails: mountain biking, horseback, running, & hiking)! Enjoy the giant soaking tub, BBQ grill, sunsets & patio. A full kitchen, sitting area, bath & BR are downstairs (550 sq. ft.). Up a 90-degree ladder to BR/retreat space, wonderful for getaway views. Our property is a 3-acre lot w/ desert flora/fauna, stars, & quietness, yet only 10 mi. from UA. Horses add to the ambiance with a taste of ranch life.

Guest favorite
The cottage exterior is showcased, surrounded by landscaped gardens featuring native plants and desert vegetation. Large windows provide natural light, while a low stone wall creates a defined border for the yard. The structure exhibits a warm adobe style under a clear blue sky.
Cottage in Oracle
4.97 out of 5 average rating, 120 reviews

A Secluded Retreat in Nature - La Casita

La Casita is nestled on 2.3 secluded acres next to the Coronado National Forest. The comfortable vintage cottage has good light and sweeping views of the foothills and woodlands around it. A beautiful garden and various outdoor sitting areas provide relaxing places to enjoy the quiet nature and many birds that live there. The Oracle Ridge trailhead to Mt. Lemmon is just a 5-minute walk from the house. These features and more are what make your stay at La Casita so enjoyable and special.

Top guest favorite
A scenic view of the Santa Catalina Mountains under a partly cloudy sky is presented. The landscape is characterized by rolling hills and desert vegetation, with a dirt road leading into the distance. The tranquil atmosphere is enhanced by the natural surroundings.
Guesthouse in Tucson
4.99 out of 5 average rating, 222 reviews

Cozy Mountain Retreat w/ Hot Tub

Come visit our small horse ranch in NW Tucson! Tucked into the foothills of the Santa Catalina Mountains, you’ll enjoy great views, and slightly cooler temperatures. You'll be close enough to town to have access restaurants,shopping, entertainment, etc, yet you'll have unlimited access to hiking and mountain biking right out our gate. * Not suitable for children under 12yrs. **This is a smoke-free property, sorry, no exceptions. *you must be able to climb a small flight of stairs*

Top guest favorite
The eastern mountains are illuminated in shades of pink and orange during sunset. The landscape is characterized by rugged mountain contours and sparse desert vegetation, capturing the tranquil beauty of the surrounding nature.
Guesthouse in Tucson
4.99 out of 5 average rating, 117 reviews

Charming Private Guesthouse with Mountain View

Check out our weekly and monthly discounts! Enjoy the beautiful mountain view from the cozy wrap around porch. Perfect for your morning coffee. Private guest house located on small horse ranch. Close to hiking, biking, and site seeing. Cozy up to the fire pit in the evening to watch the eastern mountains turn pink as the sun sets in the west. Check out our 120 plus 5 star reviews. This is truly a magical place. Non smoking of any kind, no pets, service animals, infants or children.

Guest favorite
The exterior of the rustic cabin is shown, featuring natural wood siding and a stone chimney. A wrap-around deck is visible, alongside a sturdy wooden bench. Large windows allow light into the interior, framed by trees that provide a serene backdrop.
Cabin in Mount Lemmon
4.91 out of 5 average rating, 110 reviews

Forest Hermitage With Creek. Close To Everything!

Imagine waking up to the sounds of birds chirping and the trickling of water from the creek as you sip your favorite hot drink from the balcony among the pine and fir trees. This cabin is just a stone's throw away from town center with a food shop right across the street, but is a true mountain hermitage where you can unplug and unwind from all your concerns. And with fast Wifi, you can do your best work remotely amidst the serenity of nature while a fresh mountain breeze blows.

Guest favorite
Vacation home in Tucson
4.95 out of 5 average rating, 197 reviews

Modern Loft w/ Pool & Hot Tub-Views!

Stargaze, admire the incredible mountain views & wildlife at this 2 story gated loft! Enjoy the pool table, above ground pool, hot tub, new appliances/bathroom, grill, Smart TVs, and games! Only minutes away from Tucson's popular hiking trails, 8 mins from Agua Caliente Park, 12 mins from Saguaro National Park, 15 mins from Sabino Canyon, 55 mins from Mount Lemon (a must visit!). The loft has a lot of character and is set up for only 4 guests! No parties, smoking, or gatherings.

Top guest favorite
A small casita with a peach-colored stucco exterior features a covered porch supported by wooden beams. Two light-weight chairs are positioned on the patio alongside a small table. Potted plants are arranged nearby, adding natural elements to the inviting outdoor space.
Guesthouse in Tucson
4.96 out of 5 average rating, 112 reviews

Birder AirBnB near the beautiful Catalina mnts

Small quiet casita surrounded by beautiful desert vegetation with a stunning view of the Catalina mountains. Desert wildlife frequently encountered. Near Biosphere II, hiking and biking trails, and a few small-town eateries. Near town of Oro Valley which has restaurants, a movie theater, shopping and events. Six miles N of Catalina State Park and 20 miles SW of Oracle State Park. Birdwatcher friendly with local guide available for birding tours. 1 hr. from airport.

Top guest favorite
A spacious studio features a queen-sized bed adorned with a soft coverlet. A curved red lounge chair complements the warm adobe walls and wooden ceiling beams. Natural light filters through large windows, illuminating the cozy corner with a beehive fireplace, enhancing the tranquil atmosphere.
Guesthouse in Tucson
4.96 out of 5 average rating, 875 reviews

Tucson Poet's Studio

Tucson Poet's Studio was featured in Architectural Digest (10-1-2025) “50 Best Airbnbs Across the United States", New York Magazine (6-19-2015) “Taste the Flavors of Tucson” and LivAbility (7-6-2018) “Accessible Airbnb” *NEW* EV Charger! The studio shares the private, walled courtyard and pool with the main house where my husband and I live. Located in the Peter Howell neighborhood, a convenient midtown area close to everything (2.5 mi to UA, 5 mi to downtown).

Guest favorite
Tiny home in Tucson
4.9 out of 5 average rating, 399 reviews

Little House in the Desert

Tiny Home. Very private. Peaceful and quiet. Lots of land surrounding. Separate driveway And huge lot area. Dog Ok. NO CATS New, extremely comfortable Queen memory foam/gel mattress in the bedroom and brand new Queen memory foam mattress in the pull out couch. This is the perfect little HOuse in the Desert and brand new! We are available to you and very close in the main house on the other side of the property. The houses are separated by a large brick wall.

Guest favorite
The entrance features arched doorways complemented by decorative wrought iron gates. Vibrant ceramic pots are positioned beside the entryway, set on a tiled surface that leads to the inviting interior. Lush greenery borders the walkway, enhancing the charming exterior aesthetics.
Guest suite in Tucson
4.91 out of 5 average rating, 1,172 reviews

Catalina Foothills Azul Courtyard Guest Suite

Welcome to Casita Tolsa! We are close to La Encantada Mall with Shopping, and Restaurants close by. Our Studio Guest Suite has private entrance and parking, private patio. Local Art Galleries close by with views of every mountain range and the city. Enjoy the traditional territorial style, the wood beam ceilings, the patio, the comfy foam mattress/down pillows and comforter. Our place is good for singles, couples, and business travelers.

Popular amenities for vacation rentals near Biosphere 2

  1. Airbnb
  2. United States
  3. Arizona
  4. Pinal County
  5. Oracle
  6. Biosphere 2