Guesthouse vacation rentals in Anderson County

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Top-rated guesthouse rentals in Anderson County

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

Guest favorite
Guesthouse in Anderson
Game Day Cottage in the Woods
Great location just off of I-85 at Exit 14; less than 8 miles to Clemson University, 7 miles to Green Pond Landing, and 1000 feet to Eighteen Mile Creek Boat Landing. Our cottage is located behind our home with a beautiful wooded setting. You will find a tranquil and secluded space, yet be close enough to our areas best restaurants and entertainment. We are also close enough to the Blue Ridge Mountain for a nice day trip. Please note our rate is $240 per night during Clemson home games.
$120 per night
Guest favorite
Guesthouse in Anderson
Private - Lake getaway with 7 mile view from dock
Spacious two story guest house on a private road situated on Lake Hartwell. Use the double deck dock with 7 mile view for all day fishing, swimming or just relaxing. The guest house with central heating and air is fully furnished and has a fully equipped kitchen, wifi, 3 streaming flat screen tvs, two full baths, washer/dryer combo and a large attached deck. Owners live on property but in different residence. Outdoor cameras overlook parking area. Only reserved guests have property access.
$119 per night
Guest favorite
Guesthouse in Pendleton
La Bella Farm
Do you want to be close to Clemson(11 miles), Anderson(9 miles) OR Greenville(20miles)! Do you want to just get away from all of the noise and busy life. Then you have found your spot! This is a great detached garage apartment. Settled in the quiet country side of Pendleton SC. 1 bedroom&1 bathroom with an additional sofa bed&blow up mattress. Great view of nothing but beautiful land from the kitchen window yet minutes away from Death Valley,restaurants,shopping and 85.
$75 per night

Popular amenities for Anderson County guesthouse rentals

Family-friendly guest house rentals

Guest favorite
Guesthouse in Anderson
Be Our Guest
$116 per night
Guest favorite
Guesthouse in Donalds
Home on the farm
$115 per night
Guest favorite
Guesthouse in Pelzer
South Oaks Guesthouse
$99 per night
Guest favorite
Guesthouse in Pendleton
La Bella Farm
$75 per night
Guest favorite
Guesthouse in Townville
Lisa’s Lodge
$78 per night

Guest house rentals with a patio

Guest favorite
Guesthouse in Abbeville
1-bedroom guesthouse in Abbeville, SC
$69 per night
Guest favorite
Guesthouse in Hartwell
One bedroom lake front apartment with free parking
$94 per night
Guest favorite
Guesthouse in Greenville
Finished Room over Garage (FROG) on Reedy River
$73 per night
Guest favorite
Guesthouse in Piedmont
Shou-Sugi-Ban Retreat on the Saluda River
$207 per night
Guest favorite
Guesthouse in Central
Vacation Home Clemson and Lakes
$232 per night
Guest favorite
Guesthouse in Seneca
One Particular Cove ... on Lake Hartwell
$150 per night
Guest favorite
Guesthouse in Honea Path
The Honey Flat
$89 per night
Guest favorite
Guesthouse in Greenville
Sally's Cottage
$109 per night
Guest favorite
Guesthouse in Pendleton
Nested Studio Woodscape
$135 per night
Guest favorite
Guesthouse in Clemson
Adorable Cottage 2 mi. from Death Valley
$200 per night
Guest favorite
Guesthouse in Greenville
Casita Guest House- Country Feel- Great Location
$169 per night
Guest favorite
Guesthouse in Iva
Pine Trees
$85 per night

Guest house rentals with a washer and dryer

Superhost
Guesthouse in Anderson
Farmhouse by the lake - Private guest house
$120 per night
Guest favorite
Guesthouse in Hartwell
Guest House at Lake Hartwell
$150 per night
Guest favorite
Guesthouse in Pelzer
Quaint guest cottage in Upstate
$99 per night
Guest favorite
Guesthouse in Abbeville
The Parlor Two
$90 per night
Superhost
Guesthouse in Anderson
2BR Luxe Lakeside Retreat! *17 Mins to Clemson!
$142 per night
Guest favorite
Guesthouse in Six Mile
Camper at Hickory Lodge and Guesthouse
$38 per night
Superhost
Guesthouse in Greenville
TheArk
$73 per night
Guesthouse in Clemson
Riggs Drive Gameday Getaway
$275 per night
Guest favorite
Guesthouse in Townville
Paradise Point on Lake Hartwell
$325 per night
Guesthouse in Townville
Beautiful Luxury home on Lake Hartwell by Clemson
$850 per night
Guesthouse in Clemson
Clemson Carriage House - NEW!
$148 per night
Guest favorite
Guesthouse in Iva
Pine Trees Rest
$125 per night

Destinations to explore