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Guesthouse vacation rentals in Anderson County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Anderson County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Anderson County guesthouse rentals
Family-friendly guest house rentals
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Private room in Pelzer
4.97 out of 5 average rating, 117 reviewsSouth Oaks Guesthouse
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Guesthouse in Pendleton
4.89 out of 5 average rating, 245 reviewsLa Bella Farm
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Guesthouse in Donalds
4.99 out of 5 average rating, 349 reviewsHome on the farm
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Guesthouse in Townville
4.88 out of 5 average rating, 238 reviewsLisa’s Lodge
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Guesthouse in Anderson
4.93 out of 5 average rating, 240 reviewsBe Our Guest
Guest house rentals with a patio
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Guesthouse in Greenville
4.98 out of 5 average rating, 90 reviewsFinished Room over Garage (FROG) on Reedy River
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Guesthouse in Clemson
5 out of 5 average rating, 13 reviewsAdorable Cottage 2 mi. from Death Valley
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Guesthouse in Piedmont
4.98 out of 5 average rating, 54 reviewsShou-Sugi-Ban Retreat on the Saluda River
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Guesthouse in Central
5 out of 5 average rating, 11 reviewsVacation Home Clemson and Lakes
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Guesthouse in Greenville
5 out of 5 average rating, 79 reviewsSally's Cottage
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Guesthouse in Townville
5 out of 5 average rating, 7 reviewsCharming Waterfront Guest House
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Guesthouse in Seneca
5 out of 5 average rating, 7 reviewsQuin's Lake House, Keowee. Private bottom Floor.
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Guesthouse in Pendleton
5 out of 5 average rating, 8 reviewsNested Studio Woodscape
Guest house rentals with a washer and dryer
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Guesthouse in Clemson
4.9 out of 5 average rating, 10 reviewsClemson Carriage House - NEW!
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Guesthouse in Clemson
5 out of 5 average rating, 10 reviewsRiggs Drive Gameday Getaway
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Guesthouse in Anderson
4.86 out of 5 average rating, 7 reviewsCozy 2BR lakeside apt w dock near marina & Clemson
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Guesthouse in Anderson
4.94 out of 5 average rating, 175 reviewsPrivate - Lake getaway with 7 mile view from dock
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Guesthouse in Anderson
4.86 out of 5 average rating, 177 reviewsFarmhouse by the lake - Private guest house
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Guesthouse in Townville
5 out of 5 average rating, 8 reviewsParadise Point on Lake Hartwell
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Guesthouse in Townville
4.8 out of 5 average rating, 5 reviewsBeautiful Luxury home on Lake Hartwell by Clemson
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