We’re sorry, some parts of the Airbnb website don’t work properly without JavaScript enabled.

Places to stay near Saint Louis Science Center

Book unique vacation rentals, homes, and more on Airbnb

Top-rated vacation rentals near Saint Louis Science Center

Guests agree: these stays are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

A well-lit guest room features tall vaulted ceilings with exposed wooden beams and skylights. A cozy bed is adorned with patterned bedding, while decorative plants are placed around the space. Large windows allow natural light to fill the room, complemented by soft curtains.

Home in St. Louis

4.9 out of 5 average rating, 435 reviews

Sunny South City Guest House

Newly-rehabbed & cozy guest house. Everything you need is located here in the historic Bevo Mill neighborhood. In the heart of south St. Louis city, you’re steps away from local businesses, including the picturesque, historical Das Bevo. Step into a vintage-styled oasis, featuring large windows with plenty of natural light, tall vaulted ceilings, comfy queen bed, unique fridge, breakfast bar, sizable bathroom with a large walk-in shower. Hang outside at the picnic table under cute string lights.

Top guest favorite

A living room area is furnished with a red couch, black chairs, and a coffee table. A colorful area rug covers the wooden floor, while a decorative brick fireplace with a large wall art piece provides a focal point. Natural light enters through the window, and a television is mounted on the wall.

Home in St. Louis

4.94 out of 5 average rating, 346 reviews

Art Inspired Home, Great Beds! -Near CWE/BJC/Grove

Welcome to one of STL's' most inviting & unique Airbnbs! Our home has just been completely remodeled with all the modern conveniences & is located minutes from the CWE, BJC Hospital, The Grove entertainment district, Botanical Gardens, Tower Grove Park, & so much more! The home has a rear bedroom, 1 pass-thru bedroom in the middle of the home, and a living room with 2 pull-out couches. The home includes:,W/D, yard, pond with fountains! Did I mention, Pac-man with 60 games? Come see for yourself!

A modern studio apartment is depicted, with a seating area featuring a sleek gray couch. The kitchen is visible, equipped with a refrigerator and counter space. A bed is situated in the corner, and natural light enters through the window. A workspace with a chair is also seen.

Apartment in St. Louis

4.88 out of 5 average rating, 219 reviews

Modern Studio Apartment in CWE, BJ Hospital

Welcome to St. Louis! This quiet and safe place is only minutes of walking distance to the Cathedral, Forest park, Barnes Hospital, Zoo, grocery store, and some of the finest restaurants in St. Louis. It is 6 min drive to Delmar loop/The Pageant, 8-min to Clayton, 7 min to downtown. This is a cozy studio apartment on the second floor. You will get a kitchen, dining room, and the living room, which are all clean and tidy. Metrolink stop, bus stops, are close and easy to find in the neighborhood.

Top guest favorite

A cozy living area features a modern sofa adorned with decorative pillows, complemented by stylish armchairs. A stone fireplace serves as a focal point, with a TV mounted above it. Natural light filters through window shutters, illuminating the warm wooden floor.

Apartment in St. Louis

4.91 out of 5 average rating, 194 reviews

The Boho-Grove Apartment

Enjoy a stylish experience at this centrally-located place. Warm colors and good vibes offer a retreat after a long day at work. Recharge your batteries on the ultra comfortable memory foam mattress, comfy couch with big screen, and loungy kitchen to entertain guests. If cooking is your zen, the cupboards are filled with all you need to design your next meal-creation. The Grove is in close proximity to Forest Park, BJC, Wash-U, SLU & The Central West End, Botanical Gardens & Tower Grove Park.

A modern living area features sleek furnishings, including a light gray sofa and a round wooden coffee table. A flat-screen TV is positioned on a stylish media console. The space is adorned with decorative accents, including a leafy plant and wall art, creating a comfortable atmosphere.

Apartment in St. Louis

4.88 out of 5 average rating, 119 reviews

Safe Garage Parking Stylish Apt Mins to The Zoo

Welcome to our stylish two-bedroom 2nd floor apartment in the heart of The Grove, St. Louis! Located on a quiet street just steps away from the vibrant atmosphere of The Grove district & Forest Park, it’s the perfect base for your St. Louis adventure. This unit features ultra comfortable beds, a fully equipped kitchen, and a walkable location that puts you in close proximity to the area’s best dining, nightlife, and cultural attractions. You’ll find everything you need right at your doorstep!

An open-concept living area features a dark blue couch and a granite-topped coffee table. The kitchen showcases modern appliances and seating for two. A bright bedroom contains a spacious bed, complemented by colorful artwork above it. Large windows provide natural light throughout.

Apartment in St. Louis

4.87 out of 5 average rating, 99 reviews

Welcoming Downtown West Suite- King w/ Patio (223)

Enjoy your stay in one of our corporate housing retreats! Great housing option for anyone looking to stay in town for short or long-term periods of time! Fully equipped with all of your basic amenities and a few extras! We proudly boast a comfortable and enjoyable stay, all in the heart of PRIME Central West End St Louis! This location is great for anyone who wants to be located close to: - Barnes Jewish Hospital - SLU - Wash U - The Zoo - Nightlife - Downtown festivities and so much more!!

Top guest favorite

A view from the living area into the bedroom, showcasing a serene space with a queen-size bed dressed in crisp white linens and accented by earthy throw pillows. Natural light illuminates the room, complemented by a ceiling fan and light-toned wooden flooring.

Apartment in St. Louis

4.99 out of 5 average rating, 175 reviews

The Zen Den - Centrally Located, Calm and Tranquil

The Zen Den was conceptualized out of a desire to create a calm and peaceful oasis centrally located in the North Hampton neighborhood of St. Louis where parks, cafés, restaurants, and entertainment are only minutes away. The space features modern appliances, contrasted with soft light features and natural building materials, such as reclaimed lumber, to convey a sense of calm and tranquility. Ideal for those guests seeking to retreat at the end of a busy day exploring or remote working.

Top guest favorite

A covered porch features a blend of comfortable seating arrangements and a glass-top table. Lush greenery surrounds the space, complemented by potted plants on the walls. The area is well-lit by natural light filtering through the overhead panels, creating a welcoming outdoor atmosphere.

Vacation home in St. Louis

4.96 out of 5 average rating, 150 reviews

Lovely, updated 2-bedroom apartment in The Grove

Centrally located and spacious 2nd floor apartment with private off-street parking. Updated kitchen with 2nd floor porch with bistro table. Includes Keurig coffee maker and all the basics you will need. Stackable washer/dryer. Bedroom 1 has queen bed with high thread count linens. Bedroom 2 has full bed and lots of natural light. A walk-in closet/office space. Family room is warm & inviting with Roku TV. Beautiful shared patio and fenced in backyard. Enjoy all that St. Louis has to offer!

A modern living area features a blue sofa facing a large flat-screen TV. A marble coffee table rests on a patterned rug, with a tall indoor plant adding a touch of greenery. Natural light enhances the space through multiple large windows.

Apartment in St. Louis

4.87 out of 5 average rating, 110 reviews

1 BR Loft Near Central West End, Walk to BJC

Welcome to loft luxury, walking distance to BJC, nightlife, metro station, & Whole Foods! This space includes garage parking, in-unit W/D, and everything to stay a night or a month! Other great features: - High ceilings & huge windows - Pullout couch - 55" TV - Workspace w/ fast wireless internet - Fully-equipped kitchen - Queen memory foam bed *Please note, this loft's bedroom walls don't extend to the ceiling & there is no door. Please check photos to ensure the space meets your needs!

Top guest favorite

A spacious studio apartment with yellow walls features wooden flooring and exposed beams. A dining table is set for four, while a living area includes a green recliner and a beige sofa. A queen bed is visible in the background, draped with blue curtains.

Loft in St. Louis

4.94 out of 5 average rating, 658 reviews

Historic loft living. Safe, central neighborhood

FULLY FURNISHED, cozy private studio apartment on the 3rd FL in the Southwest Gardens neighborhood next to the famous "Hill" area of South St. Louis. This elephant themed unit is walking distance from dozens of the best restaurants the area has to offer. Queen bed and love seat/fold out portable sleeps 3. *****we have 3 other private 5-star listings with the same amenities within our building. Go to my profile and scroll down to see them. We would love to host you in any of them.

A comfortable living area features a light-colored sofa adorned with green cushions. A soft area rug lies on the wooden floor, complemented by a small side table. Sunlight filters through floor-to-ceiling curtains, enhancing the serene ambiance with a potted plant in the corner.

Apartment in St. Louis

4.89 out of 5 average rating, 121 reviews

The Grove's Greenest Pad

"The Grove's Greenest Pad" A harmonious retreat located in the lively heart of the very centrally located Grove neighborhood in St. Louis. This monochromatic 1-bedroom sanctuary, only 5 minutes from SSM Hospital, immerses you in a soothing green palette, offering a refreshing escape amidst urban vibes. Explore the vibrant surroundings filled with artistic murals, eclectic eateries, and pulsating nightlife. Your tranquil, green-themed haven awaits for a unique, restorative St. Louis stay.

Top guest favorite

A brick home with a sloped roof is shown from the front, featuring a pathway lined with greenery leading to the entrance. Two chimneys rise above, and the yard is well-maintained with shrubs and flowers. The sky is partly cloudy, adding to the serene ambiance.

Guest suite in St. Louis

4.93 out of 5 average rating, 359 reviews

Home Suite Home

A NEIGHBORHOOD home with a small town vibe. NO PARTIES tolerated!!!!! OPEN ALL PHOTOS TO READ PHOTO DETAILS. A PRIVATE BASEMENT SUITE with: PRIVATE Entry, Living Room, Bedroom, Full Bath, Kitchenette, Yard/Patio; walk to Historic Route 66, restaurants, coffee shops, shopping, churches, parks/playgrounds/trails; 10-20 minutes from Lambert Airport, Downtown STL, historic neighborhoods, and major attractions; and major US Highways. *SEARCH from 3915 Watson Rd, 63109 for travel distances.

Popular amenities for vacation rentals near Saint Louis Science Center

Free parking on premises

Air conditioning

Other top sights near Saint Louis Science Center

Busch Stadium441 locals recommend

Saint Louis Zoo1,376 locals recommend

Enterprise Center183 locals recommend

Missouri Botanical Garden526 locals recommend

St. Louis Aquarium at Union Station236 locals recommend

Saint Louis Science Center283 locals recommend

Condo rentals with wifi

A modern kitchen is presented with sleek cabinetry and granite countertops. Stainless steel appliances, including a gas range and dishwasher, are visible. The open-plan layout features a cozy seating area with a sofa, and bar stools complement the kitchen island.

Condo in St. Louis

4.79 out of 5 average rating, 190 reviews

Luxury 2BD/2BH in Historic CWE/1E M

A bright bedroom displays a spacious bed adorned with white and gray bedding. A vibrant flower arrangement in a white pot is positioned on a decorative tray at the center. Light enters through a window, highlighting soft gray walls and colorful artwork.

Condo in St. Louis

4.76 out of 5 average rating, 104 reviews

Bright & Updated 1 Bedroom 1 Bath

A modern kitchen area is accented by wooden cabinetry and sleek stainless steel appliances. Two high stools are positioned at the counter, and recessed lighting casts a warm glow. The floor features rich wooden planks, enhancing the space's stylish atmosphere.

Condo in St. Louis

4.83 out of 5 average rating, 234 reviews

(First Floor) Executive Suite - Soulard District

A spacious living area is shown, featuring a large sectional couch and a dark wood coffee table placed on a light area rug. The kitchen is visible in the background, with wooden cabinetry and modern appliances. Large windows allow natural light to fill the space.

Condo in St. Louis

4.88 out of 5 average rating, 223 reviews

Forest Park Condo- Gated Parking, Walk to CWE

A living area features a comfortable gray sofa and two red accent chairs, inviting relaxation. A coffee table sits in the center, complemented by a soft area rug. Natural light filters through a window, covered by light curtains, enhancing the cozy atmosphere.

Condo in University City

4.9 out of 5 average rating, 290 reviews

Modern Condo on Delmar Loop; Central to Everything

A welcoming living area features comfortable seating with two light blue armchairs and a dark sofa. A marble fireplace serves as a focal point beneath a wall-mounted map of St. Louis. A wooden coffee table and decorative items add a cozy touch to the space.

Condo in St. Louis

4.95 out of 5 average rating, 185 reviews

Beautiful updated 2BR Charmer in CWE

Top guest favorite

The welcoming exterior of a historic brick building is showcased, featuring a red-tiled roof and large windows. A well-maintained lawn surrounds the entrance, with landscaped hedges and path lights illuminating the walkway leading to the front door.

Condo in St. Louis

4.93 out of 5 average rating, 105 reviews

Spacious | Quiet | 1 bedroom duplex with parking!

A cozy living area features a comfortable seating arrangement with a coffee table at its center. A decorative fireplace is framed by an entertainment unit with a mounted TV above. Natural light enters through the window, enhancing the space's inviting atmosphere.

Condo in St. Louis

4.87 out of 5 average rating, 124 reviews

Historic, quiet 2 Bdrm/1 bath/workspace Full Condo

Family-friendly house rentals

Home in St. Louis

4.97 out of 5 average rating, 128 reviews

The Chocolate Suite - Walkable and Peaceful

Top guest favorite

A well-lit living room features a comfortable rust-colored sofa adorned with decorative pillows. A circular glass table sits on a patterned area rug, and framed art hangs on the neutral walls. An archway leads to the dining area, enhancing the open feel of the space.

Home in St. Louis

4.96 out of 5 average rating, 128 reviews

Best of StLouis-ForestPk,Muny,Zoo,SLU/WashU,Barnes

Top guest favorite

A modern kitchen showcases white cabinetry and a spacious granite countertop with bar seating. Stainless steel appliances, including a refrigerator and dishwasher, complement the design. Natural light streams through a window, highlighting the clean, tidy environment.

Home in St. Louis

4.96 out of 5 average rating, 138 reviews

Walk to the Zoo! Newly Renovated Open Concept!

The exterior of the house is shown, featuring a white facade with black shutters. A bright yellow door serves as a focal point, complemented by two windows on either side. The sloped roof adds character to the two-story structure.

Home in St. Louis

4.87 out of 5 average rating, 975 reviews

The Little House.

A comfortable living room is showcased, featuring a large sectional sofa and a decorative stone fireplace. Colorful stained glass windows allow natural light to filter in, while a patterned area rug adds warmth to the hardwood floor.

Home in St. Louis

4.99 out of 5 average rating, 204 reviews

Sparkling Vintage Charmer, King Bed, Quiet Comfort

A well-lit bedroom features a spacious bed with soft bedding and decorative pillows. Two nightstands flank the bed, each with a lamp. A stylish rug lies beneath the bed, and artwork adorns the wall. Natural light filters in through the window, covered by navy curtains.

Home in St. Louis

4.96 out of 5 average rating, 118 reviews

Roomy Oasis with hot tub on the Hill!

The exterior of a classic two-story brick home is shown, featuring a charming front porch with decorative railings and steps leading to the entrance. Leafless trees create a serene atmosphere, while light filters through the branches, highlighting the home's architectural details.

Home in St. Louis

4.9 out of 5 average rating, 213 reviews

Botanical Gardens Bliss

The exterior of a modern home is showcased, featuring a striking combination of light and dark siding. A flight of steps leads to the front door, surrounded by large windows that provide a bright and open feel. Green grass and small trees add a touch of greenery.

Home in St. Louis

4.9 out of 5 average rating, 101 reviews

Beautiful Modern 3BR in the Grove / ABODEbucks

Apartment rentals with air conditioning

A contemporary living area features a gray sofa and an accent chair with a glass coffee table at the center. Natural light filters through numerous windows, illuminating the space. A dining area is visible in the background, complete with a wooden table and stylish chairs.

Apartment in St. Louis

4.82 out of 5 average rating, 211 reviews

Gorgeous condo in HEART of STL! Gourmet kitchen✨

Top guest favorite

An outdoor seating area features several cushioned chairs arranged around a coffee table, situated on a paved surface. Lush greenery surrounds the area, while a wooden staircase leads to an elevated deck, softly illuminated by string lights above.

Apartment in St. Louis

4.98 out of 5 average rating, 424 reviews

Large, Woodsy, Warm and Inviting | Cozy 2BR Apt

Top guest favorite

The living area features a mix of modern design and comfort. A sleek, brown sofa is paired with a stylish armchair adorned with a black and white throw pillow. A glass coffee table displays magazines, while the kitchen area with bar seating is visible in the background.

Apartment in St. Louis

4.95 out of 5 average rating, 443 reviews

Trendy Soulard area One Bedroom Apartment

The entrance features a pair of white double doors, framed by vibrant green plants and bright pink flowers. Steps lead up to the door, flanked by yellow flower planters on either side, set against a backdrop of a red brick façade.

Apartment in St. Louis

4.79 out of 5 average rating, 120 reviews

Eagles Nest @ McPherson House!

Top guest favorite

A cozy living area features grey walls and stylish furnishings, including a dark leather sofa and a matching armchair. A geometric area rug adds subtle color underfoot. Natural light shines through the window, and a piece of wall art adds character to the space.

Apartment in St. Louis

4.97 out of 5 average rating, 230 reviews

Cozy 1BR Apartment the "Ferner Flatette"

The exterior of a two-story studio is surrounded by lush greenery, including tall banana plants and colorful foliage. A set of steps leads up to the entrance, which is partially shaded by overhanging branches and offers a glimpse of the building's wooden facade.

Apartment in St. Louis

4.97 out of 5 average rating, 544 reviews

Charming Cozy Studio Suite

A spacious bedroom features a metal frame bed dressed in neutral tones, accompanied by two bedside tables with lamps. Above the bed, minimalist artwork decorates the wall, while a round mirror reflects natural light. Warm wooden flooring adds a cozy touch.

Apartment in St. Louis

4.75 out of 5 average rating, 239 reviews

Comfortable + Lovely Spot at Tower Grove Park

A cozy living room features exposed brick walls and a ceiling fan. A spacious sofa is positioned near a window, accompanied by a comfortable chair and an accent table. A patterned area rug lies on the wooden floor, adding warmth to the inviting space.

Apartment in St. Louis

4.87 out of 5 average rating, 323 reviews

We do Italian STL style. Perfecto! Enjoy our NBHD!

Other great vacation rentals near Saint Louis Science Center

Top guest favorite

A bright studio apartment features a spacious bed with neutral linens, complemented by two decorative pillows. A comfortable sofa sits nearby, and framed artwork adorns the walls. A modern light fixture hangs from the ceiling, providing soft illumination throughout the space.

Apartment in St. Louis

4.92 out of 5 average rating, 91 reviews

Bella Nido

Top guest favorite

A comfortable living area features a light-colored sofa and a mid-century chest below a wall-mounted TV. Natural light fills the space through large, arched windows, dressed in elegant maroon curtains. A small dining table for four, adorned with tableware, adds to the inviting atmosphere.

Home in St. Louis

5 out of 5 average rating, 18 reviews

Gibson Estate: Timeless 2BR haven in the Grove

The kitchen and living area feature a modern design complemented by rustic wooden beams. A spacious island with seating is positioned in front of stainless steel appliances and a sleek countertop. Natural light enters through windows, illuminating the cozy sitting area facing a large screen television.

Guest suite in St. Louis

4.89 out of 5 average rating, 46 reviews

CWE Historic Modern Newly Renovated Large Basement

The front exterior of the cottage features a welcoming entrance with wooden steps leading to a white door. Lush green grass surrounds the home, complemented by flower beds and a clay pot. A fenced yard provides a sense of privacy.

Cottage in St. Louis

4.8 out of 5 average rating, 485 reviews

"HILL" COTTAGE"

A tranquil bedroom is presented with a plush queen bed featuring soft linens and decorative pillows. Natural light filters through a nearby window, highlighting warm earthy tones. A stylish ceiling fan and two lamps provide additional illumination. An accent mirror and greenery enhance the inviting atmosphere.

Apartment in St. Louis

4.85 out of 5 average rating, 13 reviews

Cozy Art Retreat |Balcony, Wi‑Fi, BJC, Walk to CWE

A charming two-story building features a white facade with arched doorways. The entrance is accessed by a set of stairs, with decorative trim framing the windows on either side. The steps are bordered by small shrubs, and the sky above displays soft clouds.

Apartment in St. Louis

4.89 out of 5 average rating, 178 reviews

Cozy Hideaway: Your Home Away!

The exterior of the house features a welcoming front porch with wooden railings and steps leading to a vibrant blue door. Landscaping includes neatly arranged stones and shrubs, contributing to the home's overall charm.

Home in St. Louis

4.88 out of 5 average rating, 41 reviews

Arch City Escape

A spacious living area features hardwood flooring and a cozy fireplace. A comfortable sofa and wooden coffee table are positioned near a rustic accent wall. The open kitchen is visible in the background, and large artwork depicting wildlife enhances the decor.

Apartment in St. Louis

4.95 out of 5 average rating, 97 reviews

Soulard Lodge/Queen/Fast WiFi/5 Min to DT/Laundry

Destinations to explore