Panama vacation rentals
Book unique homes, vacation rentals, and more on Airbnb
Top-rated vacation rentals in Panama
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama vacation rentals
Panama beach vacation rentals
Apartment in Panamá
4.95 out of 5 average rating, 161 reviewsModern apt ocean view in heart of Panamá yoo tower
Home in Bocas del Toro Province
4.87 out of 5 average rating, 113 reviewsCasa Clearwater... Your Caribbean Dream
Apartment in Panamá
4.81 out of 5 average rating, 110 reviewsBest View In Panama! Best Located Unique Full Apt.
Loft in Río Hato
4.87 out of 5 average rating, 146 reviewsDisfruta del Mar y de una Experiencia inolvidable
Condo in Maria Chiquita
4.85 out of 5 average rating, 431 reviewsRelaxation by the sea
Home in Playa Venao
4.9 out of 5 average rating, 115 reviewsBeautiful Home Directly on Playa Venao Sleeps 8-10
Condo in San Carlos District
4.95 out of 5 average rating, 140 reviewsPunta Caelo beachfront apartment San Carlos
Apartment in Panama City
4.96 out of 5 average rating, 54 reviewsJacuzzi inside colonial ruins in beautiful apartme
Panama house rentals
Home in Taboga Island
4.97 out of 5 average rating, 143 reviewsCasa Rosie - Taboga dream home
Home in Altos del Maria
4.79 out of 5 average rating, 242 reviewsModern House in Altos del Maria, Panama
Home in Los Algarrobos
4.99 out of 5 average rating, 119 reviewsNew house! 5 min from David on the Boquete highway
Home in El Valle de Antón
4.93 out of 5 average rating, 120 reviewsRustic family mountain home - 5 min walk to town!
Home in Panamá
4.93 out of 5 average rating, 299 reviewsEstudio Privado a 10 Min del Aeropuerto !
Home in Bocas del Toro District
4.82 out of 5 average rating, 107 reviewsAmazing over the water house
Home in Vista Mar Golf, Beach & Marina
4.88 out of 5 average rating, 226 reviewsLuxurious Beach House - Private Pool Golf & Marina
Home in Bajo Boquete
4.81 out of 5 average rating, 110 reviewsSecluded Riverfront Home - Boquete area with Pool
Beach house rentals in Panama
Home in Colón Island
4.83 out of 5 average rating, 101 reviewsBeautiful Two bedroom Apartment over the Caribbean
Home in contadora
4.86 out of 5 average rating, 195 reviewsvilla in contadora, las perlas
Home in playa coronado
4.8 out of 5 average rating, 112 reviewsBeach Villa in Coronado
Home in Playa Mata Oscura
4.92 out of 5 average rating, 25 reviewsCasa De Ola, Jungle Beach Cabin
Home in Bocas del Toro
4.9 out of 5 average rating, 10 reviewsLa Casita Barrbra BnB
Home in Playa Venao
5.0 out of 5 average rating, 17 reviewsCasa Samambaia - sea view tropical paradise w pool
Home in Chame
5.0 out of 5 average rating, 12 reviewsP/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath
Home in San Carlos
4.93 out of 5 average rating, 88 reviewsBeach House-Ocean View Rooftop Jacuzzi & Pool
Your guide to Panama
All About Panama
A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.
The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.
The best time to stay in a vacation rental in Panama
The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.
Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.
Top things to do in Panama
Casco Viejo
As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.
Panama Canal
When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.
Bocas Del Toro
Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.
Destinations to explore
- Bungalow rentals Panama
- Rentals with a fire pit Panama
- Pet-friendly rentals Panama
- Rentals with an accessible height bed Panama
- Nature eco lodge rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Townhouse rentals Panama
- Bed and breakfasts Panama
- Rentals with breakfast Panama
- Loft rentals Panama
- Beach condo rentals Panama
- Rentals with a patio Panama
- Chalet rentals Panama
- Rentals with beach access Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Boutique hotel rentals Panama
- Hotel rentals Panama
- Cottage rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Vacation home rentals Panama
- Rentals with a hot tub Panama
- Wheelchair accessible rentals Panama
- Fitness-friendly rentals Panama
- Rentals with pools Panama
- Treehouse rentals Panama
- Beach house rentals Panama
- Tiny house rentals Panama
- Rentals with a home theater Panama
- Condo rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Monthly Rentals Panama
- Farmstay rentals Panama
- Rentals with a fireplace Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Rentals with lake access Panama
- Waterfront rentals Panama
- Rentals with a sauna Panama
- Boat rentals Panama
- Villa rentals Panama
- Apartment rentals Panama
- House rentals Panama
- Island rentals Panama
- Kid-friendly rentals Panama
- Family-friendly rentals Panama
- Smoking-friendly rentals Panama
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes