Vacation home rentals in Panama
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Top-rated vacation home rentals in Panama
Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama vacation home rentals
Family-friendly vacation home rentals
Vacation home in Juan Gallego
4.84 out of 5 average rating, 80 reviewsPebos Reef, 12 guests, Amazing views!!
Vacation home in El Chirú
4.85 out of 5 average rating, 20 reviewsApartment in Buenaventura
Vacation home in La Pintada
4.38 out of 5 average rating, 16 reviewsLa Pintada Inn hotel complete for private group
Vacation home in Panamá
Lovely place with exclusive private pool
Vacation home rentals with a patio
Vacation home in Anton Valley
4.91 out of 5 average rating, 43 reviewsAdorable 2 bedroom home near India Dormida hiking
Vacation home in Rio Hato
4.83 out of 5 average rating, 6 reviewsOcean view studio Town Center Playa Blanca Rio Hat
Vacation home in Volcán
4.82 out of 5 average rating, 33 reviewsBeautiful cabin with balcony
Vacation home in Bocas del Toro
4.58 out of 5 average rating, 40 reviewsPrivate Luxury Over the Water Bungalow
Vacation home in Maria Chiquita
4.95 out of 5 average rating, 21 reviewsPlaya Escondida, Apt with Spectacular Ocean View
Vacation home in San Carlos
4.87 out of 5 average rating, 31 reviewsWelcome to our house in Playa Corona
Vacation home in San Carlos
5.0 out of 5 average rating, 7 reviewsSpectacular three-bedroom beach friendly
Vacation home in Bajo Boquete
4.67 out of 5 average rating, 21 reviewsVILLA 70 IN BOQUETE VALLE ESCONDIDO RESORT & SPA
Vacation home rentals with a washer and dryer
Vacation home in Bocas del Toro Province
4.85 out of 5 average rating, 20 reviewsBeautiful 2 bedroom open air home jungle home
Vacation home in Arraiján
4.79 out of 5 average rating, 48 reviewsApartment In Club De Playa, with Pool and BBQ
Vacation home in Coronado
4.9 out of 5 average rating, 31 reviewsModern Beach House With Private Beach Access
Vacation home in Chitré
4.94 out of 5 average rating, 35 reviewsCASA EdditA ° Cozy house in Chitre
Vacation home in Maria Chiquita
4.84 out of 5 average rating, 37 reviewsPlaya Escondida apt 200 mt2, 4r 4b waterfront
Vacation home in Playa Blanca Rio Hato
4.72 out of 5 average rating, 29 reviewsComfortable apartment with pool and close to the beach
Vacation home in Bajo Boquete
4.8 out of 5 average rating, 20 reviewsVilla Alejandro -Junior Suite with private kitchen
Vacation home in Cambutal
4.82 out of 5 average rating, 11 reviewsTreetop 2 bedroom apartment close to the beach
Destinations to explore
- Bungalow rentals Panama
- Rentals with a fire pit Panama
- Pet-friendly rentals Panama
- Rentals with an accessible height bed Panama
- Nature eco lodge rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Townhouse rentals Panama
- Bed and breakfasts Panama
- Rentals with breakfast Panama
- Loft rentals Panama
- Beach condo rentals Panama
- Rentals with a patio Panama
- Chalet rentals Panama
- Rentals with beach access Panama
- Cabin rentals Panama
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- Boutique hotel rentals Panama
- Hotel rentals Panama
- Cottage rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama
- Rentals with a hot tub Panama
- Wheelchair accessible rentals Panama
- Fitness-friendly rentals Panama
- Rentals with pools Panama
- Treehouse rentals Panama
- Beach house rentals Panama
- Tiny house rentals Panama
- Rentals with a home theater Panama
- Condo rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Monthly Rentals Panama
- Farmstay rentals Panama
- Rentals with a fireplace Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Rentals with lake access Panama
- Waterfront rentals Panama
- Rentals with a sauna Panama
- Boat rentals Panama
- Villa rentals Panama
- Apartment rentals Panama
- House rentals Panama
- Island rentals Panama
- Kid-friendly rentals Panama
- Family-friendly rentals Panama
- Smoking-friendly rentals Panama
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- Family travel hub Tips and inspiration
- Family budget travel Get there for less
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- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes