Villa vacation rentals in Panama
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Top-rated villa rentals in Panama
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Panama villa rentals
Villa rentals with a pool
Villa in Las Escobas del Venado
4.95 out of 5 average rating, 21 reviewsBreathtaking Ocean Villa. Casa de Vida
Jun 9 – 16
Villa in Lagartero
5.0 out of 5 average rating, 11 reviewsPrivate Villa with private pool, in Santa Catalina
Dec 26 – Jan 2
Villa in Chame
4.82 out of 5 average rating, 55 reviewsOcean Waves Villa (C6-1D) 2 bed, 2 bath
Jun 18 – 25
Villa in Playa Venao
4.86 out of 5 average rating, 14 reviewsVilla Best Located in Blue | With Private Pool
Jun 24 – Jul 1
Villa in Río Grande
4.94 out of 5 average rating, 49 reviewsCheerful 3 bedroom countryside Villa with pool.
Oct 6 – 13
Villa in PA
4.8 out of 5 average rating, 71 reviewsVilla Estrella in Playa Venao
Jul 3 – 10
Villa in Playa Venao
4.92 out of 5 average rating, 24 reviewsVilla La Piragua : 3BR Surfside Retreat : 5-7G
Oct 18 – 25
Villa in Pedasí
4.85 out of 5 average rating, 13 reviewsDrone Pedasi Ranch - Beach Pool Folks Fest Fishing
Oct 21 – 28
Private villa rentals
Villa in Bocas del Toro
5.0 out of 5 average rating, 56 reviewsCasa del Mar - eco aqua villa
Nov 26 – Dec 3
Villa in Saboga
5.0 out of 5 average rating, 7 reviewsSaboga: El Remanso Beachfront Entire Upper Level
Aug 17 – 24
Villa in Bocas del Toro
5.0 out of 5 average rating, 15 reviewsCasa de Mono Open Air 3 Bedroom Apartment
Sep 13 – 20
Villa in Bajo Boquete
4.94 out of 5 average rating, 62 reviewsSpacious Villa on a Coffee Farm 5 mins from town!
Sep 21 – 28
Villa in Anton Valley
4.95 out of 5 average rating, 39 reviewsQuinta El Bosque
Jan 27 – Feb 3
Villa in Santiago
4.89 out of 5 average rating, 36 reviewsThe Terraces of Playa Morrillo
May 11 – 18
Villa in Paso Ancho
4.96 out of 5 average rating, 72 reviewsCharming & Enjoyable Cabin surrounded by trees
Jun 3 – 10
Villa in Boca Chica
4.95 out of 5 average rating, 80 reviewsSand Dollar Villa by the sea at Boca Chica Panama
Nov 13 – 20
Luxury villa rentals
Villa in Panamá
5.0 out of 5 average rating, 30 reviewsBreathtaking Views Mansion w/King Beds
Sep 29 – Oct 6
Villa in Bocas del Toro Province
4.88 out of 5 average rating, 43 reviewsLuxury Villa Rainforest Estate with Pool
May 25 – Jun 1
Villa in Punta Chame
4.93 out of 5 average rating, 14 reviewsFREE NIGHT Amazing Beachfront Villa - Palm House
Nov 26 – Dec 3
Villa in Río Hato
4.91 out of 5 average rating, 22 reviewsSecluded Villa in Buenaventura Golf and Resort
May 25 – Jun 1
Villa in Cañas
5.0 out of 5 average rating, 15 reviewsResidence Denter Tumas
May 10 – 17
Villa in Juan Gallego
4.83 out of 5 average rating, 12 reviewsFantastic Villa in KasaKai
Aug 31 – Sep 7
Villa in Panamá
4.73 out of 5 average rating, 11 reviewsIncredible Hacienda with ocean and river View
Sep 10 – 17
Villa in Isla Colon
4.8 out of 5 average rating, 5 reviewsCasa Caracola. Luxury villa. 200 mts from beach
Nov 9 – 16
Destinations to explore
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