Villa vacation rentals in Isle of Palms
Find and book unique villas on Airbnb
Top-rated villa rentals in Isle of Palms
Guests agree: these villas are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Isle of Palms villa rentals
Villa rentals with a pool
Villa in Seabrook Island
4.83 out of 5 average rating, 59 reviewsPrivate island villa with luxury resort amenities!
Villa in Saint Helena Island
4.99 out of 5 average rating, 81 reviewsSandy Toes Condos
Villa in Saint Helena Island
4.99 out of 5 average rating, 71 reviewsLittle Palm Villa | Oceanfront
Villa in Seabrook Island
5.0 out of 5 average rating, 13 reviewsClose to beach, pools, tennis& golf+Amenity Card*
Villa in Seabrook Island
4.91 out of 5 average rating, 32 reviewsUpscale Villa, Amenity Included! Dog Friendly
Villa in Seabrook Island
4.86 out of 5 average rating, 36 reviewsSeabrook Golf View Villa: Pickleball, Pool & Bike
Villa in Seabrook Island
4.93 out of 5 average rating, 55 reviewsNewly Remodeled Villa, 5 Minute Walk to Beach
Villa in Seabrook Island
4.95 out of 5 average rating, 60 reviewsBeautiful and Spacious 2 Bedroom Courtside Villa!
Private villa rentals
Villa in Seabrook Island
4.67 out of 5 average rating, 9 reviewsBeach and Golf Paradise | Vaughan Villa
Villa in Kiawah Island
4.93 out of 5 average rating, 97 reviewsClean & Comfortable! Steps to the beach!
Villa in Kiawah Island
4.96 out of 5 average rating, 98 reviewsSpacious new 2BR Villa across beach near Sanctuary
Villa in Edisto Island
4.74 out of 5 average rating, 54 reviewsLoft-e-Lagoon *No Cleaning Fee*
Villa in Edisto Island
4.97 out of 5 average rating, 37 reviewsRelax in a Happy Place
Villa in Kiawah Island
4.97 out of 5 average rating, 88 reviewsLagoon view villa with office, easy walk to beach!
Villa in Isle Of Palms
4.77 out of 5 average rating, 39 reviews7C Seagrove - Sweetgrass
Villa in Seabrook Island
5.0 out of 5 average rating, 6 reviewsSecluded Villa by Sea Free Amenity Cards Included
Luxury villa rentals
Villa in Seabrook Island
4.92 out of 5 average rating, 13 reviewsLuxury Seabrook Isl Beach Condo
Villa in Kiawah Island
5.0 out of 5 average rating, 26 reviewsOcean Front! Beach is steps away. Clean and Crisp!
Villa in Seabrook Island
Seaside Therapy - An iTrip Vacations Home
Villa in Isle of Palms
4.78 out of 5 average rating, 27 reviewsBeachfront IOP Villa with Outdoor Pool. Remodeled!
Villa in Kiawah Island
5.0 out of 5 average rating, 16 reviewsOceanfront Windswept Villa
Villa in Isle of Palms
5.0 out of 5 average rating, 4 reviewsOceanfront Villa in Wild Dunes! Community Pool!
Villa in Johns Island
5.0 out of 5 average rating, 3 reviews3 Bedroom 2 Bath Duneloft Villa! Neighborhood Pool
Villa in Kiawah Island
4.89 out of 5 average rating, 18 reviewsSpacious Penthouse 3BR 3Bath Villa with Ocean View
Quick stats about villa rentals in Isle of Palms
Total rentals
70 properties
Rentals with dedicated workspaces
40 properties have a dedicated workspace
Rentals with a pool
70 properties have a pool
Family-friendly rentals
60 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
$170 before taxes and fees
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- Monthly Rentals Isle of Palms
- Rentals with a hot tub Isle of Palms
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