Guesthouse vacation rentals in Charleston County

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Popular amenities for Charleston County guesthouse rentals

Family-friendly guest house rentals

Guest favorite

Guesthouse in Charleston

4.91 out of 5 average rating, 675 reviews

Island Oasis—Near Downtown

EricRating, 5 stars3 weeks ago
Chris’s place is perfect for a couple looking to travel to the Charleston area. Close to the county park and a short drive to downtown Charleston. Would definitely stay here again
Guest favorite

Guesthouse in Charleston

4.95 out of 5 average rating, 363 reviews

The White House of Avondale

TracixRating, 5 stars3 days ago
We really enjoyed our stay here! The apartment has been updated since the ad photos were taken. Furniture, linens, & decor are all different & make for a cohesive “old timey, cottage at the beach” vibe. There are beautiful details like the lovely ceiling tiles & an antique looking map of Charleston on the living room wall. My husband loved the sponges & coral decor pieces. The ad photos show window A/C units…they have been removed & there is a regular main unit instead. It kept the apt nice & cool! The apt has lots of windows (w/pull down privacy shades) & the bed was extremely comfortable. If it’s cool outside, one could have a lie-in, with the windows open for a relaxing, lazy breeze. Everything was VERY clean. (No need to do a wipe down before settling in.) The shower was fabulous! Great water pressure & plenty of hot water. Craig was a wonderful host and made everything smooth, easy, and welcoming. We would love to stay here again on our next trip to Charleston!
Guest favorite

Guesthouse in Mount Pleasant

4.97 out of 5 average rating, 237 reviews

Bungalow Under The Oaks

MicheleRating, 5 stars1 month ago
This bungalow was perfect for me and my 2 little dogs. Everything we needed was there, the yard was clean and secure. We felt safe, it was quiet and set back from the road. We will definitely return for our next visit to Mt Pleasant. Thank you, we all enjoyed your cozy bungalow under the oaks! Michele, Holly and Benji
Guest favorite

Guesthouse in Summerville

4.87 out of 5 average rating, 766 reviews

New Loft in Historic Summerville

RonnieRating, 5 stars2 weeks ago
We appreciated the ease of booking and checking in at The Loft. Jacquelynn has everything streamlined from the start to the end of your stay. The unit is well organized and very clean. We especially enjoyed being able to open the cellular shade from the top and view the top branches of the large old trees against the sky- so peaceful. Overall, this is a lovely spot to stay in.
Guest favorite

Guesthouse in Mount Pleasant

4.94 out of 5 average rating, 244 reviews

Green Garden Studio @greengardenstudio2017

VirginiaRating, 5 stars2 weeks ago
We will definitely stay here again! Within 15 minutes of King Street and the garage apartment was so precious!
Guest favorite

Guesthouse in Summerville

4.95 out of 5 average rating, 233 reviews

Nina's Cottage -Historic Downtown Summerville

KimberlyRating, 5 stars2 weeks ago
This place is a gem in a beautiful town! We walked easily to the town center several times during our stay, and enjoyed the Saturday morning market. Enjoying the mornings and evenings on the huge screened-in porch was a treat. We look forward to returning.
Guest favorite

Guesthouse in Charleston

5 out of 5 average rating, 103 reviews

Liz Lane Cottage- entire guesthouse

JamieRating, 5 stars1 week ago
Definition of southern hospitality! The cottage was both spacious and spotless. Host was incredibly responsive and made everything leading up to our stay a breeze! Cottage was so well stocked and all of our bedding was luxe and very comfortable! Less than 15 minutes from the heart of Charleston! Would not only recommend, I hope to visit again soon 😊
Guest favorite

Guesthouse in Charleston

4.99 out of 5 average rating, 278 reviews

Spacious Daniel Island Apartment

AndrewRating, 5 stars3 days ago
Such a great experience. David was so awesome. He made sure we had everything we needed and was so helpful with great places to eat. The neighborhood is one of the most tranquil, beautiful and safe places ever. Definitely recommend staying here. We will be back

Guest house rentals with a patio

Guest favorite

Guesthouse in Mount Pleasant

4.96 out of 5 average rating, 99 reviews

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

PolinaRating, 5 stars4 weeks ago
Great place to stay at! A few min drive to downtown, and very close to the beach. Close to very good restaurants, breakfast and coffee spots, supermarkets.... everything you need!
Guest favorite

Guesthouse in Goose Creek

5 out of 5 average rating, 27 reviews

Dreams

ColleenRating, 5 stars4 days ago
Soooo comfortable! I specifically looked for a place to stay that my 82 yr old father would be comfortable in. A lot of places go with cheaper "fashionable" furniture that only a 20-something year old would find simple and cool looking...but inevitably is uncomfortable. The reclining leather couches where very nice and comfortable for him. I couldn't see staying in a hotel room with just a bed and an office chair for him to sit on (6ft 2in tall & wouldn't want to be gone from room all day & night like we had planned. He would go on some outings, but not all. The beds, bedding and pillows where VERY soft and comfortable! The bed I slept in was wonderful, not too soft, not too firm. The kitchen was stocked with more than we needed. The shower was larger than any stall I have been in, the shower head was LOVELY and water pressure was AWESOME! I WOULD DEFINATELY recommend Fernando as a wonderful host and he has made a great place to stay.
Guest favorite

Guesthouse in Charleston

4.98 out of 5 average rating, 43 reviews

1/1 sleeps 3 ADU Modern+Amazing!

JacobRating, 5 stars2 weeks ago
Very clean and quiet. Great location between Folly Beach and Downtown
Superhost

Guesthouse in Charleston

4.79 out of 5 average rating, 135 reviews

Guest Suite by the Beach

AnnaRating, 5 stars1 week ago
We loved staying at Tyler’s place! The suite has a private entry with a full bath, a half bath, washer/dryer, bedroom, a baby changing station, and a mini fridge/coffee maker. Our toddler absolutely loved the backyard with the play set! It was perfect for our small family’s needs and just a short drive to the beach. Clean and lovely!
Guest favorite

Guesthouse in Charleston

4.95 out of 5 average rating, 100 reviews

Spacious 1 bedroom cottage in Avondale

RyanRating, 5 stars1 month ago
Nice place to stay in Charleston. Short walk to Avondale, cheap Uber ride downtown and back, not too far from the beach. Airbnb had everything I needed.
Guest favorite

Guesthouse in North Charleston

4.91 out of 5 average rating, 115 reviews

My Happy Place

SenecaRating, 5 stars1 day ago
It is one of the most adorable and charming guest houses I have ever had the pleasure of staying in. The backyard is absolutely stunning, with a beautiful pool, lime trees, and palm trees. It is truly a magical place.
Guest favorite

Guesthouse in Charleston

4.99 out of 5 average rating, 115 reviews

The James: “Tiny” Home b/w Downtown & Folly

LaceyRating, 5 stars4 days ago
Caitlin did an amazing job with her guesthouse! It’s absolutely stunning. The attention to detail was crazy. This is a perfect place for pups as well. Caitlin left two bones and a handwritten note card for us when we arrived. We come to Charleston frequently and will be staying here from now on!!
Guest favorite

Guesthouse in Johns Island

4.89 out of 5 average rating, 145 reviews

Cozy Cottage! 5 mins from Kiawah!

JeasonRating, 5 stars1 week ago
Amazing place! Great people and location of the house. Everything in the area was close as well as the beach!

Guest house rentals with a washer and dryer

Guest favorite

Guesthouse in Charleston

4.85 out of 5 average rating, 114 reviews

CHS Guest house w/ Pool & Hot Tub on Golf Course

TrevorRating, 5 stars3 weeks ago
Alicia and family were fantastic hosts. They communicated with me from beginning to end and were very proactive. The space was very clean and tidy. They also provided a great deal of amenities and we felt right at home. Would not mind staying again if I ever found myself in their area again.
Guest favorite

Guesthouse in Mount Pleasant

4.99 out of 5 average rating, 140 reviews

Beach, downtown, Alhambra Hall weddings so close!

MichaelRating, 5 stars5 days ago
It’ll be tough to beat this Airbnb in the future! We visit Charleston every year and have been doing Airbnb’s instead of hotels for a while now and this is the nicest one yet. We know the area well from 30 years of visiting and this place and the location make a great base of operations. The full size refrigerator was a nice plus-no buying ice for the cooler all week(or stealing from hotels😈)! This garage apartment, if you can call it that, is the size of a small home and has everything you need including a washer and dryer which was nice, so we didn’t have to stay up later when we got home washing clothes. Will definitely look at staying here in the future.
Guest favorite

Guesthouse in Charleston

4.9 out of 5 average rating, 587 reviews

Cute, Cozy, Charleston Cottage

MattRating, 5 stars4 days ago
This is a cozy and safe space! It’s easy to find and located in a quiet neighborhood. The space inside is ideal for a couple of nights exploring the local area!
Guest favorite

Guesthouse in Charleston

5 out of 5 average rating, 240 reviews

James Island "La Casita" Nestled btw Beach & City

MichaelRating, 5 stars1 month ago
Such a lovely place--a charming, peaceful neighborhood, friendly neighbors; hands-down, the nicest AirBnB we've ever rented. We were not ready to leave. Yes, La Casita Blanco felt like home--cozy, contemporary, spotlessly clean with an extremely comfortable mattress; a beautiful place overall. John and family were THE sweetest. There was not one leaf unturned in their lovely garage apartment. They even provided fresh eggs from their chickens and a fresh pitcher of filtered water in the refrigerator. A nicely presented information book is placed by the front door; many have mentioned the parking pass for various parks and beaches. We were visiting family and unable to take advantage of the many amenities of the island, but the area is replete with numerous activities and eateries. John thoughtfully called to inform us of the electrical outage post storm, and discussed options in case the power was not restored in a timely manner. This was a perfect getaway!
Guest favorite

Guesthouse in Summerville

4.97 out of 5 average rating, 239 reviews

Summerville’s Tiny Oak Hideaway

CaseyRating, 5 stars1 week ago
Great location and space!
Guest favorite

Guesthouse in Charleston

4.96 out of 5 average rating, 134 reviews

Beach/Downtown 10min

DillonRating, 5 stars1 week ago
Erin’s place is great! I felt right at home, it was very clean, and it’s a very reasonable price. It has my recommendation, I’ll definitely be back!
Guest favorite

Guesthouse in Mount Pleasant

4.97 out of 5 average rating, 444 reviews

Guesthouse Convenient to Charleston, Shem Creek, and Beaches

TracyRating, 5 stars1 week ago
Great spot for checking out Mount Pleasant, Charleston, Folly Beach, Sullivans Island, and Isle of Palms. We made Lots of great day trips, Angel Tree, Patriots Point, Boone Plantation and Charleston (Rainbow Row, Pineapple Fountain, City Market and checking out the beautiful homes). Lots of great local places eat that aren’t so tourist like. Thanks Sean and Rebecca for the Treehouse comforts during our visit! Would come back and or recommend!
Guest favorite

Guesthouse in Charleston

4.98 out of 5 average rating, 143 reviews

Charleston Casita near Folly Beach *Dog Friendly*

NatalieRating, 5 stars1 week ago
All though well-kept on the outside. This is a don't judge a book by its cover for us. To experience beautiful lights @James Island County Park during the Thanksgiving/Christmas, especially when all is full. Honestly, Great Place. It's a 9 min drive to state park, 5 min to everything else, doctors, restaurant's, grocery, ext. We are patients @ MUSC Hospital & travel yearly for annual visit. Comfort, safety & convivence checks the list here. Surprisingly clean for a place that allows animals for we do not travel with one & was a little worried. Kitchen is modern & fully stocked, bathroom modern, clean & stocked. Bed, comfortable with clean sheets. Tv's available in room & Livingroom included cable and streaming. Everything is up to date & they responded quickly & friendly. Nice to stay in a home where you can feel they put effort into your comfort & needs. Thank you*

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