Guesthouse vacation rentals in Charleston
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Top-rated guesthouse rentals in Charleston
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Charleston guesthouse rentals
Family-friendly guest house rentals
Guesthouse in North Charleston
4.94 out of 5 average rating, 351 reviewsCozy Park Circle, Charleston Guest House
Guesthouse in Charleston
4.92 out of 5 average rating, 309 reviewsMother in Law in James Island Riverland Terrace
Guesthouse in Charleston
4.91 out of 5 average rating, 654 reviewsIsland Oasis—Near Downtown
Guesthouse in Summerville
4.94 out of 5 average rating, 215 reviewsNina's Cottage -Historic Downtown Summerville
Guesthouse in Mount Pleasant
4.99 out of 5 average rating, 100 reviews5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!
Guesthouse in Charleston
4.93 out of 5 average rating, 320 reviewsCozy Island Cottage
Guesthouse in Johns Island
4.98 out of 5 average rating, 242 reviewsPrivate waterfront apt in the oaks
Guesthouse in North Charleston
4.86 out of 5 average rating, 447 reviewsPark Circle Jungalow Loft
Guest house rentals with a patio
Guesthouse in Charleston
4.96 out of 5 average rating, 132 reviewsStudio Apartment Minutes to Downtown Charleston
Guesthouse in Charleston
4.98 out of 5 average rating, 128 reviewsPrivate Backyard With Fire Pit, 15 Min to Downtown
Guesthouse in Johns Island
4.91 out of 5 average rating, 115 reviewsCozy Cottage! 5 mins from Kiawah!
Guesthouse in Hanahan
4.99 out of 5 average rating, 84 reviewsThe Violet Villa w/ no cleaning fee
Guesthouse in Charleston
4.94 out of 5 average rating, 82 reviewsSpacious 1 bedroom cottage in Avondale
Guesthouse in Charleston
4.95 out of 5 average rating, 95 reviewsBoHo styled casita in adorable neighborhood...
Guesthouse in Charleston
5.0 out of 5 average rating, 27 reviews1/1 sleeps 3 ADU Modern+Amazing!
Guesthouse in Mount Pleasant
5.0 out of 5 average rating, 32 reviewsCoastal Charm: Village Hideaway
Guest house rentals with a washer and dryer
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 120 reviewsBeach, downtown, Alhambra Hall weddings so close!
Guesthouse in North Charleston
4.94 out of 5 average rating, 119 reviewsNewly Renovated Studio in Park Circle
Guesthouse in Charleston
4.9 out of 5 average rating, 556 reviewsCute, Cozy, Charleston Cottage
Guesthouse in Summerville
4.97 out of 5 average rating, 221 reviewsTiny Oak Cottage in Historic Downtown Summerville
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 260 reviews#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
Guesthouse in Charleston
5.0 out of 5 average rating, 222 reviewsJames Island "La Casita" Nestled btw Beach & City
Guesthouse in Charleston
4.98 out of 5 average rating, 246 reviewsDetached Guest Suite
Guesthouse in Mount Pleasant
4.98 out of 5 average rating, 443 reviewsOld Mt. Pleasant/Shem Creek close to Sullivans/DT
Quick stats about guesthouse rentals in Charleston
Total rentals
230 properties
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Rentals with a pool
10 properties have a pool
Pet-friendly rentals
50 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
23K reviews
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