Guesthouse vacation rentals in San Diego County
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in San Diego County
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for San Diego County guesthouse rentals
Family-friendly guest house rentals
Guesthouse in San Diego
4.92 out of 5 average rating, 245 reviewsNorth Park Garden Studio
Guesthouse in San Diego
4.88 out of 5 average rating, 185 reviewsSerene San Diego Canyon Getaway
Guesthouse in Chula Vista
4.95 out of 5 average rating, 480 reviewsPrivate Casita in Great Eastlake Neighborhood
Guesthouse in Oceanside
4.92 out of 5 average rating, 266 reviewsThe Sunshine House. Location, Location, Ocean.
Guesthouse in San Diego
4.93 out of 5 average rating, 451 reviewsPrivate Cottage in Walkable North Park w/AC
Guesthouse in San Diego
4.97 out of 5 average rating, 297 reviewsPrivate Guest House with a View
Guesthouse in San Diego
4.96 out of 5 average rating, 255 reviewsYour Kensington Bungalow
Guesthouse in Encinitas
4.96 out of 5 average rating, 348 reviewsCardiff by the Sea Beach Bungalow
Guest house rentals with a patio
Guesthouse in La Mesa
4.98 out of 5 average rating, 255 reviewsLa Mesa Suite
Guesthouse in San Diego
4.99 out of 5 average rating, 155 reviewsAdorable cottage in Talmadge
Guesthouse in La Mesa
4.97 out of 5 average rating, 138 reviewsDa Hui Hut-Beachy home/La Mesa’s best view and spa
Guesthouse in San Diego
4.92 out of 5 average rating, 155 reviewsCentral studio w/ private outdoor space & parking
Guesthouse in Spring Valley
4.97 out of 5 average rating, 116 reviewsLoft Cabin-Night Cinema+Hot Soaking Tub+Views!
Guesthouse in La Mesa
4.99 out of 5 average rating, 175 reviewsSDCannaBnB #1 *420 *parking *dog-friendly *hot tub
Guesthouse in San Diego
5.0 out of 5 average rating, 114 reviewsSantorini-Inspired Cottage #1 w/ Hot Tub + Views
Guesthouse in San Diego
4.98 out of 5 average rating, 129 reviewsPrivate Studio Cottage with Outdoor Patio
Guest house rentals with a washer and dryer
Guesthouse in San Diego
4.9 out of 5 average rating, 198 reviewsSTUNNING Casita with a View!!
Guesthouse in Valley Center
4.92 out of 5 average rating, 214 reviewsNorth San Diego Serenity
Guesthouse in Encinitas
4.99 out of 5 average rating, 150 reviewsCoastal Farm Sanctuary Stay. 20 min to the Beach.
Guesthouse in San Diego
4.98 out of 5 average rating, 120 reviewsCasita Hermosa - Close to everything in San Diego
Guesthouse in San Diego
4.95 out of 5 average rating, 216 reviewsPrivate beach guesthouse w/ private parking
Guesthouse in San Diego
4.83 out of 5 average rating, 214 reviewsCozy Cottage
Guesthouse in San Diego
4.96 out of 5 average rating, 461 reviewsStorybook house private Studio
Guesthouse in San Diego
4.87 out of 5 average rating, 421 reviewsThe Golden Hill mosaic "casita"
Destinations to explore
- House rentals United States
- Guesthouse rentals United States
- House rentals San Diego
- Guesthouse rentals San Diego
- Guesthouse rentals California
- House rentals California
- House rentals Joshua Tree
- Guesthouse rentals Palm Springs
- House rentals Palm Springs
- Fitness-friendly rentals San Diego County
- Beachfront rentals San Diego County
- Smoking-friendly rentals San Diego County
- Townhouse rentals San Diego County
- Bungalow rentals San Diego County
- Rentals with a washer and dryer San Diego County
- Condo rentals San Diego County
- Family-friendly rentals San Diego County
- Rentals with lake access San Diego County
- Farmstay rentals San Diego County
- Campsite rentals San Diego County
- Rentals with pools San Diego County
- Rentals with a sauna San Diego County
- Luxury rentals San Diego County
- House rentals San Diego County
- Rentals with a kayak San Diego County
- Waterfront rentals San Diego County
- Vacation home rentals San Diego County
- Tiny house rentals San Diego County
- Wheelchair accessible rentals San Diego County
- Villa rentals San Diego County
- Bed and breakfasts San Diego County
- Serviced apartment rentals San Diego County
- Rentals with an accessible height toilet San Diego County
- Rentals with a balcony San Diego County
- Private suite rentals San Diego County
- Cabin rentals San Diego County
- Loft rentals San Diego County
- Tent rentals San Diego County
- Rentals with a fireplace San Diego County
- Monthly Rentals San Diego County
- Rentals with a fire pit San Diego County
- Apartment rentals San Diego County
- Cottage rentals San Diego County
- Rentals with outdoor seating San Diego County
- Rentals with a hot tub San Diego County
- Rentals with a patio San Diego County
- Rentals with breakfast San Diego County
- Rentals with an EV charger San Diego County
- Resort rentals San Diego County
- Rentals with a home theater San Diego County
- RV rentals San Diego County
- Rentals with an accessible height bed San Diego County
- Hotel rentals San Diego County
- Kid-friendly rentals San Diego County
- Rentals with beach access San Diego County
- Rentals with a beach view San Diego County
- Pet-friendly rentals San Diego County
- Cabins United States
- Treehouses United States
- Glamping United States
- Tiny Houses United States
- Beach Houses United States
- Campers and RVs United States
- Lakehouses United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Family travel hub Tips and inspiration
- Family budget travel Get there for less
- Vacation ideas for any budget Make it special without making it spendy
- Travel Europe on a budget How to take the kids to Europe for less
- Outdoor adventure Explore nature with the family
- Bucket list national parks Must-see parks for family travel
- Kid-friendly state parks Check out these family-friendly hikes