I'm originally from Texas and currently live in NYC. I often travel for work, but also try to mix in a leisure trip here and there. I've found that Airbnb is a great way to meet natives and get the local feel of each city.
To date I've used Airbnb to rest my head in: Philadelphia, Austin, Sankt Gallen, Munich, Salzburg, Prague, Berlin, and Saint Lucia. I've met many great people, swapped some great stories, and created a few new ones.