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Panama vacation rentals

Book unique homes, vacation rentals, and more on Airbnb

Top-rated vacation rentals in Panama

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Guest favorite
Cottage in Bocas del Toro Province
Rustic cottage-Ocean views/walk to surfing/Jungle
Casa Palmera is located near the only beach to the north/west side of Isla Carenero, with a beautiful ocean view where the sun sets in a secluded and peaceful area. Only a 5 minute walk to the Carenero Surf Break . Restaurants are within walking distance, hike around the island, or use the kayaks and see the beauty. We are 5 minute boat taxi away from the main town of Bocas, but everything you need to make your vacation unforgettable is on this island! Drinking water included.A/C in bedrooms
Nov 20 – 27
$110 per night
4.96 out of 5 average rating, 165 reviews
Guest favorite
Home in Bocas del Toro District
Orange House - Over The Water Rentals
Enjoy golden sunsets across the bay from the Orange House at Over The Water Rentals. Home away from home in a tropical paradise. Relax on your outdoor lounge or explore the bay. The house has snorkel gear, SUP's & kayaks for guests to use for free. Bikes can be rented. Located close to town & airport in a quiet local neighborhood. The house features a king size master bedroom & queen guest room, spacious hot water shower, handmade organic toiletries, fully equipped kitchen & high speed wifi
Oct 6 – 13
$124 per night
4.93 out of 5 average rating, 191 reviews
Guest favorite
Guesthouse in Torio
Torio guesthouse with panoramic view
Our private guesthouse is suspended over the Torio River, on the west coast of the Azuero Peninsula. It is a paradise for hikers, bird watchers, surfers and beach goers. Marked trails with posted maps begin at our place. Hike to a beautiful waterfall, mountain or beach. Photograph birds from the porch. Surf, body board and swim safely (no strong currents). Walk to good restaurants, and a small grocery. Experienced Surfers have Morrillo Beach and Playa Reina. Watch sun and moon rise.
Dec 10 – 17
$67 per night
4.91 out of 5 average rating, 106 reviews

Popular amenities for Panama vacation rentals

Panama house rentals

Guest favorite
Home in Pedasí
3 min to Pedasi, 5 min to the Beach, Private Pool!
Oct 10 – 17
$149 per night
4.93 out of 5 average rating, 106 reviews
Guest favorite
Home in Panamá
Private Studio 10 Min from the airport !
May 1 – 8
$36 per night
4.93 out of 5 average rating, 287 reviews
Superhost
Home in El Valle de Antón
Casa Antares
Feb 11 – 18
$37 per night
4.81 out of 5 average rating, 117 reviews
Guest favorite
Home in Las Colinas de Caceres de Arraijan
Tropical Haven with Yoga Platform
Sep 28 – Oct 5
$275 per night
4.98 out of 5 average rating, 195 reviews
Guest favorite
Home in El Valle de Antón
Rustic family mountain home - 5 min walk to town!
May 7 – 14
$97 per night
4.93 out of 5 average rating, 112 reviews
Superhost
Home in Bajo Boquete
Secluded Riverfront Home - Boquete area with Pool
Nov 17 – 24
$79 per night
4.81 out of 5 average rating, 105 reviews
Guest favorite
Home in Bocas del Toro
La Casita Barrbra BnB
Apr 22 – 29
$161 per night
5.0 out of 5 average rating, 5 reviews
Guest favorite
Home in Playa Venao
Casa Samambaia - sea view tropical paradise w pool
Jul 4 – 11
$272 per night
5.0 out of 5 average rating, 13 reviews
Guest favorite
Home in San Carlos
Beach House-Ocean View Rooftop Jacuzzi & Pool
Nov 19 – 26
$226 per night
4.93 out of 5 average rating, 83 reviews
Guest favorite
Home in Pedasí
Ocean View From The Jungle!
Jul 31 – Aug 7
$339 per night
5.0 out of 5 average rating, 5 reviews
Guest favorite
Home in Costa Esmeralda
Beach House-Amazing Pool, Surf & Pet Friendly
Dec 6 – 13
$152 per night
4.96 out of 5 average rating, 98 reviews
Guest favorite
Home in Panamá
Spacious accommodation with ocean views
Sep 13 – 20
$168 per night
4.94 out of 5 average rating, 53 reviews

Panama condominium rentals

Guest favorite
Condo in San Carlos District
Punta Caelo beachfront apartment San Carlos
Aug 18 – 25
$140 per night
4.95 out of 5 average rating, 133 reviews
Guest favorite
Condo in Panama
Patty’s Cozy & Quiet Studio with K-bed in Casco
Sep 16 – 23
$86 per night
4.99 out of 5 average rating, 200 reviews
Guest favorite
Condo in Panamá
Spacious Executive Apartment
Aug 17 – 24
$86 per night
4.92 out of 5 average rating, 132 reviews
Guest favorite
Condo in Panamá
Excellent complete apartment, Panamá, Panamá
Dec 15 – 22
$192 per night
4.97 out of 5 average rating, 145 reviews
Guest favorite
Condo in Panama City
Park View Luxury Apartment
Jan 7 – 14
$130 per night
4.9 out of 5 average rating, 194 reviews
Guest favorite
Condo in Chame
Exclusive Beachfront apartment 1Hour from Pma City
Jul 16 – 23
$132 per night
4.96 out of 5 average rating, 135 reviews
Superhost
Condo in Maria Chiquita
Relaxation by the sea
Nov 22 – 29
$66 per night
4.85 out of 5 average rating, 424 reviews
Guest favorite
Condo in Panamá
Cozy two bedroom apartment
Dec 17 – 24
$78 per night
4.82 out of 5 average rating, 118 reviews
Guest favorite
Condo in Nueva Gorgona
Beautiful Apartment of Playa-PH Royal Palm-Gorgona
Apr 17 – 24
$80 per night
4.93 out of 5 average rating, 146 reviews
Guest favorite
Condo in Panamá
Luxury apartment in the heart of Casco Antiguo
$83 per night
4.83 out of 5 average rating, 168 reviews
Superhost
Condo in Panamá
Cozy Unit with Balcony in Santa Ana, Casco Viejo
Jan 6 – 13
$49 per night
4.9 out of 5 average rating, 118 reviews
Guest favorite
Condo in Panama
Playa apartment with pool and slides!
Sep 20 – 27
$84 per night
4.94 out of 5 average rating, 172 reviews

Other great vacation rentals in Panama

Guest favorite
Earthen home in playa el arenal pedasi
Earth House Pedasi Experience
Jul 1 – 8
$53 per night
4.96 out of 5 average rating, 113 reviews
Superhost
Apartment in Panamá
Design Pool and 180º Rooftop N3
May 10 – 17
$85 per night
4.83 out of 5 average rating, 120 reviews
Guest favorite
Farm stay in Bajo Boquete
Casitas in Butterfly and Honey Farm
Jan 12 – 19
$130 per night
4.91 out of 5 average rating, 144 reviews
Superhost
Bungalow in Bocas del Toro
Romantic Over the Water Bungalow with Floating Bed
Nov 2 – 9
$150 per night
4.89 out of 5 average rating, 125 reviews
Guest favorite
Apartment in Panamá
Chic Studio in Casco Antiguo - View to Main Plaza
Sep 16 – 23
$96 per night
4.9 out of 5 average rating, 355 reviews
Superhost
Cabin in Panamá Oeste
Cabaña Mirador by Casa Amaya
Apr 25 – May 2
$54 per night
4.8 out of 5 average rating, 210 reviews
Guest favorite
Townhouse in Panama
Unique Historic House in Casco
Aug 30 – Sep 6
$563 per night
4.94 out of 5 average rating, 126 reviews
Guest favorite
Cabin in Torio
Cozy open space, unique jungle views, river access
Sep 27 – Oct 4
$102 per night
4.98 out of 5 average rating, 90 reviews
Guest favorite
Apartment in Panamá
Cozy n Comfy con balcón in the heart of Casco
Nov 23 – 30
$102 per night
5.0 out of 5 average rating, 51 reviews
Guest favorite
Apartment in Panamá
Superb Apartment In The Center Of Panama City
Jul 9 – 16
$68 per night
4.96 out of 5 average rating, 55 reviews
Superhost
Villa in Bocas del Toro
Bocas del toro - Villa over the water- Bahia Coral
Oct 6 – 13
$330 per night
4.86 out of 5 average rating, 29 reviews
Guest favorite
Cabin in Chame
Las Nubes En Chica
May 9 – 16
$81 per night
4.89 out of 5 average rating, 56 reviews

Your guide to Panama

All About Panama

A narrow isthmus on the southern tip of Central America, Panama is the cultural gateway to South America and the geographical gateway between the Caribbean Sea and the Pacific Ocean. Panama City, its stunning capital city, juxtaposes old-quarter Casco Viejo against the shiny, soaring skyscrapers of the modern district — all surrounded by rolling green hills and vast blue ocean studded with tiny islands. The Metropolitan Natural Park, a wildlife refuge threaded through with hiking trails, is just 10 minutes away from downtown. And Taboga Island, a volcanic enclave featuring a rich array of plants as well as white-sand beaches, is easily reachable via a 30-minute ferry ride.

The terrain rises dramatically from white-sand Caribbean beaches to lush mountain jungles. Near the top of the country, altitude-wise, you’ll find Boquete, home to world-renowned coffee plantations, and the Quetzal Trail, one of Panama’s most scenic hiking trails. Leaving from Volcan Baru National Park, it passes through the Talamanca Mountain Range, where you’ll discover rare tropical wildlife including spider monkeys, tapir, and brightly colored frogs.


The best time to stay in a vacation rental in Panama

The lovely tropical climate makes the prospect of securing a vacation rental in Panama appealing all year long. The drier winter months are ideal for hitting the country’s hiking trails or visiting the beaches. Many of the country’s most significant religious festivals, including Carnaval and Semana Santa (Holy Week), occur in March and April. You’ll want to keep this in mind when booking your Panama house rental if you are headed to a city that hosts a big celebration.

Once Panama’s rainy season starts in May, the sunshine is interrupted with short bursts of heavy rain. It is also usually the quietest time of year for tourism, and you may find yourself alone in the country’s national parks or beaches. That all changes, of course, after the rainy season finishes in November and gorgeous, sunny weather returns.


Top things to do in Panama

Casco Viejo

As the oldest part of Panama City, settled in 1673, Casco Viejo is filled with beautifully restored French and Spanish-style buildings, with a touch of art deco flair. As you stroll down the cobblestone streets, past pastel-colored buildings housing trendy restaurants, upscale bars, and inviting coffee shops, time seems to shimmer between the 19th and 21st centuries. Explore the neighborhood during the day; return after dark for its lively nightlife.

Panama Canal

When the 51-mile Panama Canal opened in 1914, it provided a waterway through Central America and reduced the traveling distance between the Pacific and Atlantic Ocean by 8,000 miles. The impact that this had on global commerce is hard to underestimate. The Pacific mouth of the canal is 26 miles outside Panama City, making it easy to visit this engineering marvel and watch as enormous ships rise and descend through a series of locks.

Bocas Del Toro

Lying close to the border of Costa Rica, this collection of islands is Panama's most popular beach destination. Largely undeveloped, the islands are home to lush tropical rainforest. Great snorkeling and diving opportunities abound in the Isla Bastimentos National Park, which is home to a wide variety of Caribbean coral species as well as (gentle) nurse sharks, crab, and stingrays.

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