La Mesa vacation rentals

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Top-rated vacation rentals in La Mesa

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

Guest favorite

Guesthouse in La Mesa

4.92 out of 5 average rating, 204 reviews

Fig Tree Bungalow

Enjoy your stay in San Diego in this newly renovated guesthouse. Centrally located about a mile from Hwy 8, Hwy 125, and the Grossmont Trolley Station & Transit Center. Only a 15-20 minute drive to downtown, the airport, the beaches, and most of San Diego's other popular tourist attractions. This cozy, two-story, detached unit is located behind my home, and has its own private entrance and partitioned yard for your enjoyment. There's plenty of street parking directly in front of the house.

Aug 29 – Sep 5

$107 per night
Guest favorite

Home in La Mesa

4.84 out of 5 average rating, 171 reviews

Newer "Manor Studio"

Centrally located in San Diego County this brand new studio style unit has a private entrance, private patio area and street parking. Furnished with a queen size bed, love seat, full bathroom and kitchen area. One large drawer to accommodate personal items, and a wall rack to hang clothing. There is a smart TV with WiFi streaming capabilities and lots of USB plugs to charge your devices. On street parking in front of unit (no parking in driveway). No Pets allowed. No Hair Dying allowed.

Jun 11 – 18

$96 per night
Guest favorite

Guest suite in La Mesa

4.85 out of 5 average rating, 101 reviews

Cozy Unique Studio/One Bedroom Gem

Relax and renew at this unique and tranquil one bedroom/studio with queen bed. Comfortable and private, with an enclosed personal deck area. Includes a kitchen with an oven, full sink, refrigerator, microwave, coffee maker, and cookware/plates/utensils. Wall mounted TV with ROKU service. Bathroom with full tub. Complimentary coffee, snacks, and a pound of Starbucks coffee. Newly installed A/C unit. Gated off-street parking. No smoking in unit. Smoking is permitted on the patio. No pets.

Nov 7 – 14

$113 per night

Popular amenities for La Mesa vacation rentals

Stay near La Mesa's top sights

Grossmont Center48 locals recommend
Mt. Helix Park92 locals recommend
Lake Murray Community Park11 locals recommend
DZ Akins24 locals recommend
La Mesa Springs Shopping Center7 locals recommend
Trader Joe's52 locals recommend

Other great vacation rentals in La Mesa

Guest favorite

Guest suite in San Diego

4.97 out of 5 average rating, 145 reviews

Guesthouse near SDSU in Upscale Area - Cal King

Jul 30 – Aug 6

$101 per night
Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 243 reviews

Hawks nest

Aug 7 – 14

$159 per night
Guest favorite

Guesthouse in El Cajon

4.96 out of 5 average rating, 129 reviews

Mt Helix Studio Loft with Mountain Views

Apr 28 – May 5

$106 per night
Guest favorite

Guesthouse in La Mesa

4.9 out of 5 average rating, 140 reviews

La Cabana

Nov 20 – 27

$140 per night
Guest favorite

Guesthouse in La Mesa

4.98 out of 5 average rating, 242 reviews

La Mesa Suite

May 29 – Jun 5

$180 per night
Guest favorite

Guesthouse in La Mesa

4.93 out of 5 average rating, 135 reviews

Granny Flat with Bedroom/Bathroom/Kitchen

Oct 5 – 12

$99 per night
Guest favorite

Guesthouse in La Mesa

4.97 out of 5 average rating, 165 reviews

Cozy Coop with a View

Aug 3 – 10

$140 per night
Guest favorite

Guesthouse in La Mesa

4.98 out of 5 average rating, 126 reviews

Da Hui Hut-Beachy home/La Mesa’s best view and spa

Aug 24 – 31

$151 per night
Superhost

Condo in La Mesa

4.92 out of 5 average rating, 119 reviews

La Mesa Village Condo ~ SDSU, Beaches, Downtown

Jul 29 – Aug 5

$142 per night
Guest favorite

Guesthouse in San Diego

4.91 out of 5 average rating, 111 reviews

Charming Granny Flat Near SDSU & Transit Center

Apr 30 – May 7

$87 per night
Guest favorite

Apartment in La Mesa

4.94 out of 5 average rating, 286 reviews

A Little Bit of Luxury in La Mesa! Private & Gated

Oct 7 – 14

$137 per night
Guest favorite

Guesthouse in San Diego

4.9 out of 5 average rating, 186 reviews

STUNNING Casita with a View!!

May 12 – 19

$110 per night

Other great vacation rentals in La Mesa

Guest favorite

Guesthouse in La Mesa

4.87 out of 5 average rating, 180 reviews

(2) US Entire upstairs Apartment MT HELIX

Jul 23 – 30

$128 per night
Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 58 reviews

Private 1 BR Paradise retreat

Dec 9 – 16

$111 per night
Guest favorite

Guest suite in La Mesa

5.0 out of 5 average rating, 30 reviews

Emerald King Wellness Suite w/ Sauna & Workspace

Aug 7 – 14

$122 per night
Guest favorite

Home in La Mesa

4.96 out of 5 average rating, 52 reviews

Cozy, Single Bedroom, Detached Guest House

Oct 16 – 23

$118 per night
Guest favorite

Tiny home in La Mesa

5.0 out of 5 average rating, 92 reviews

Casita de Pueblo - Private Yard, La Mesa Village

Oct 18 – 25

$114 per night
Superhost

Tiny home in La Mesa

4.85 out of 5 average rating, 34 reviews

Tiny House of Tiny Things

Aug 17 – 24

$90 per night
Guest favorite

Guest suite in La Mesa

4.86 out of 5 average rating, 78 reviews

La Mesa Granny Flat

Nov 9 – 16

$95 per night
Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 30 reviews

Sunny La Mesa Hilltop Cottage

Apr 23 – 30

$119 per night
Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 37 reviews

Beautiful Bright Mt. Helix Studio

Dec 13 – 20

$115 per night
Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 45 reviews

ino Mt. Helix

Jan 22 – 29

$122 per night
Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 53 reviews

Cozy Casita with Perfect Patio

Jun 9 – 16

$86 per night
Guest favorite

Guesthouse in La Mesa

4.9 out of 5 average rating, 63 reviews

Modern La Mesa Village Stay at Casa de Mesa

May 29 – Jun 5

$131 per night

Quick stats about vacation rentals in La Mesa

Total rentals

540 properties

Rentals with dedicated workspaces

320 properties have a dedicated workspace

Rentals with a pool

150 properties have a pool

Pet-friendly rentals

170 properties allow pets

Family-friendly rentals

260 properties are a good fit for families

Total number of reviews

22K reviews

Frequently Asked Questions

  • Are there pet-friendly vacation rentals in La Mesa?

    Four-legged friends are welcome in La Mesa. Choose from more than 170 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in La Mesa?

    Yes! Work meets play with ease at over 320 vacation rentals in La Mesa featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there La Mesa vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 150 vacation homes with pools in La Mesa, available on Airbnb. Make a splash and soak up the sun in style!

  • Do house rentals in La Mesa have a bbq area?

    Absolutely! We offer over 80 house rentals with a bbq area in La Mesa. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in La Mesa have a gym?

    Absolutely! We offer over 30 house rentals with a gym in La Mesa. Enjoy a tailored experience with all the comforts you desire.

  • How much does it cost to stay in guesthouse rentals in La Mesa?

    Experience the best of La Mesa with our guesthouse rentals, starting at about $50 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there family-friendly townhouse rentals in La Mesa?

    La Mesa has more than 10 family-friendly townhouse rentals. Amenities on the property may include high chairs, travel cribs, or strollers.

  • Do house rentals in La Mesa have wifi?

    Absolutely! We offer over 290 house rentals with wifi in La Mesa. Enjoy a tailored experience with all the comforts you desire.

  • Do townhouse rentals in La Mesa have air conditioning?

    Absolutely! We offer over 20 townhouse rentals with air conditioning in La Mesa. Enjoy a tailored experience with all the comforts you desire.

  • What are the most popular amenities for Apartment Rentals in La Mesa?

    Enhance your stay in our Apartment Rentals with the most popular amenities: over 50 homes with wifi, over 30 homes with air conditioning, and more. Indulge in the ultimate retreat, tailored to your preferences.

Destinations to explore

  1. Airbnb
  2. United States
  3. California
  4. San Diego County
  5. La Mesa