La Mesa vacation rentals

Book unique vacation rentals, houses, and more on Airbnb

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Popular amenities for La Mesa vacation rentals

Stay near La Mesa's top sights

Grossmont Center48 locals recommend
Mt. Helix Park92 locals recommend
Trader Joe's52 locals recommend
Lake Murray Community Park11 locals recommend
DZ Akins24 locals recommend
La Mesa Springs Shopping Center7 locals recommend

Other great vacation rentals in La Mesa

Guest favorite
Home in La Mesa
Clean 1BR/1BA Guest House Peaceful Private Casita
Apr 9 – 16
$117 per night
4.96 out of 5 average rating, 480 reviews
Guest favorite
Guesthouse in La Mesa
(2) US Entire upstairs Apartment MT HELIX
Apr 10 – 17
$103 per night
4.87 out of 5 average rating, 180 reviews
Guest favorite
Guesthouse in La Mesa
La Cabana
Feb 3 – 10
$140 per night
4.9 out of 5 average rating, 140 reviews
Guest favorite
Guesthouse in La Mesa
Cozy Coop with a View
Jul 8 – 15
$140 per night
4.97 out of 5 average rating, 163 reviews
Guest favorite
Bungalow in La Mesa
Two bedroom garden bungalow in West La Mesa
Oct 27 – Nov 3
$130 per night
4.93 out of 5 average rating, 191 reviews
Guest favorite
Guesthouse in La Mesa
Spacious, private Mt. Helix country style studio
Nov 18 – 25
$119 per night
4.99 out of 5 average rating, 242 reviews
Guest favorite
Cottage in La Mesa
La Mesa House On a Hill With Mountain Views!
May 22 – 29
$140 per night
4.97 out of 5 average rating, 274 reviews
Superhost
Guesthouse in San Diego
Studio w/private entrance by SDSU, updated in 2023
Aug 1 – 8
$83 per night
4.85 out of 5 average rating, 131 reviews

Other great vacation rentals in La Mesa

Guest favorite
Guest suite in La Mesa
"NEW" SWEET AND COZY CACTUSVILLE STUDIO SAN DIEGO
Apr 19 – 26
$96 per night
4.99 out of 5 average rating, 159 reviews
Guest favorite
Home in La Mesa
Cozy, Single Bedroom, Detached Guest House
Feb 11 – 18
$110 per night
4.96 out of 5 average rating, 50 reviews
Guest favorite
Guest suite in La Mesa
Emerald King Wellness Suite w/ Sauna & Workspace
Aug 24 – 31
$122 per night
5.0 out of 5 average rating, 30 reviews
Guest favorite
Guesthouse in La Mesa
Private 1 BR Paradise retreat
Feb 8 – 15
$111 per night
5.0 out of 5 average rating, 58 reviews
Guest favorite
Guesthouse in La Mesa
Modern La Mesa Village Stay at Casa de Mesa
Mar 28 – Apr 4
$118 per night
4.9 out of 5 average rating, 62 reviews
Superhost
Tiny home in La Mesa
Tiny House of Tiny Things
Jun 15 – 22
$100 per night
4.85 out of 5 average rating, 34 reviews
Guest favorite
Guesthouse in La Mesa
Beautiful Bright Mt. Helix Studio
Nov 10 – 17
$117 per night
5.0 out of 5 average rating, 36 reviews
Guest favorite
Guesthouse in La Mesa
ino Mt. Helix
Jan 22 – 29
$122 per night
5.0 out of 5 average rating, 43 reviews

Quick stats about vacation rentals in La Mesa

Total rentals

540 properties

Rentals with dedicated workspaces

320 properties have a dedicated workspace

Rentals with a pool

150 properties have a pool

Pet-friendly rentals

170 properties allow pets

Family-friendly rentals

260 properties are a good fit for families

Total number of reviews

22K reviews

Frequently Asked Questions

  • Are there pet-friendly vacation rentals in La Mesa?

    Four-legged friends are welcome in La Mesa. Choose from more than 170 vacation rentals for guests traveling with pets.

  • Are there vacation rentals with a dedicated workspace in La Mesa?

    Yes! Work meets play with ease at over 320 vacation rentals in La Mesa featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there La Mesa vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 150 vacation homes with pools in La Mesa, available on Airbnb. Make a splash and soak up the sun in style!

  • Do house rentals in La Mesa have a bbq area?

    Absolutely! We offer over 70 house rentals with a bbq area in La Mesa. Enjoy a tailored experience with all the comforts you desire.

  • Do house rentals in La Mesa have a gym?

    Absolutely! We offer over 30 house rentals with a gym in La Mesa. Enjoy a tailored experience with all the comforts you desire.

  • How much does it cost to stay in private suite rentals in La Mesa?

    Experience the best of La Mesa with our private suite rentals, starting at about $40 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Are there family-friendly apartment rentals in La Mesa?

    La Mesa has more than 20 family-friendly apartment rentals. Amenities on the property may include high chairs, travel cribs, or strollers.

  • Do villa rentals in La Mesa have wifi?

    Absolutely! We offer over 10 villa rentals with wifi in La Mesa. Enjoy a tailored experience with all the comforts you desire.

  • Do villa rentals in La Mesa have air conditioning?

    Absolutely! We offer over 10 villa rentals with air conditioning in La Mesa. Enjoy a tailored experience with all the comforts you desire.

  • What are the most popular amenities for Villa Rentals in La Mesa?

    Enhance your stay in our Villa Rentals with the most popular amenities: over 10 homes with air conditioning, over 10 homes with wifi, and more. Indulge in the ultimate retreat, tailored to your preferences.

Destinations to explore

  1. Airbnb
  2. United States
  3. California
  4. San Diego County
  5. La Mesa