Vacation home rentals in Missouri

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in Missouri

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

A spacious open-concept living area is shown, featuring a cozy seating arrangement with two sofas and a chair. A coffee table is centered on a decorative area rug. Natural light enters through windows, and the kitchen is visible in the background, showcasing a dining area.

Vacation home in Lebanon

Shouse 2 bed/2 bath near Bennett Spring Lebanon MO

Have fun with the whole family at this stylish shouse. Close to Bennett Spring State Park, this super modern shop house is perfect for family vacations & couples get aways. Out door fire-pit overlooks a field full of deer almost every evening. 2 bedrooms each have their own full baths. Common area has full kitchen & laundry room. Wi-fi & parking! Feel like you are in the country, yet close to town for any essentials! Super clean / modern. Close to Lake of the Ozarks, FT Leonard Wood & Rolla

LocationFamilyComfort

4.93 out of 5 average rating, 120 reviews

Superhost

The exterior of a single-story home is displayed, showcasing a combination of stone and siding. A welcoming porch with wooden steps leads to the entrance. Lush landscaping surrounds the driveway, and a spacious area for parking is visible beside the garage.

Vacation home in Springfield

Happy Trails Duplex

Brand new, open floor plan in a quiet neighborhood. Located in southwest Springfield. You would be hard pressed to find a cleaner home anywhere! Each room is furnished with 3 smart tvs for viewing your own subscriptions, comfortable queen sized beds and plenty of storage. Conveniently located to local shopping and dining. The home also has beautiful walking trails across the street to enjoy nature as well as an 18 hole golf course 3 blocks away. You can rest assure you will feel right at home!

LocationFamilyCleanliness

4.86 out of 5 average rating, 21 reviews

Top guest favorite

The exterior of the green house displays a modern design with a metal roof and large windows. A covered porch extends from the front, featuring railings and outdoor seating. Lush greenery surrounds the structure, enhancing the natural setting.

Vacation home in Highlandville

Two Rivers Guest House (no cleaning fee)

Please read thoroughly: Bike to Two Rivers Mountain Bike Park for a morning ride or relax in a comfortable space after a late evening at Greenhouse Two Rivers. Our place is perfectly situated between the two! This newly constructed private retreat space is conveniently located between between Springfield and Branson. Enjoy relaxing on the spacious deck overlooking the woods, book a blacksmithing or enameling class with us, or use our place as a base while you explore Springfield or Branson.

ValueLocationKitchen

4.99 out of 5 average rating, 153 reviews

Guest favorite

A colorful cabin with a purple exterior is set beside a calm lake. Decking leads to the water, framed by trees displaying autumn foliage. Two purple chairs are positioned outside the entrance, providing a scenic view of the lake and surrounding nature.

Vacation home in Camdenton

Lilac Lodge-A Perfect Lake Destination!

If you want expansive views on deep calm water, close to town, this is your Ticket! Have fun water play, fishing or just relaxing on the wrap around deck while charcoal grilling and boat watching. Includes a one well conc dock with a 10X28 slip, swim platform & ladder. It's gentle grassy yard is great for kids and pets play. Newer decks/railings, paint in & out, carpet, Bdrm & LR furniture, TVs, and fiber internet. This Cute, Quirky Cabin is a Fun-Affordable get away. Create a Memory!

LocationFamilyCondition

4.88 out of 5 average rating, 93 reviews

Top guest favorite

A spacious living area is highlighted by two sectional sofas arranged around a textured rug. A mounted television is centrally positioned above a modern electric fireplace. Large windows provide natural light, showcasing colorful foliage outside. The bar area is visible in the background.

Vacation home in Hermann

Hermann Whitetail Farmhouse

A modern farmhouse-styled rental home located south of historic Hermann, Missouri. Full use of large acreage property with lake area surrounded by forest. Quiet and secluded, but within minutes of downtown Hermann. Full kitchen, multiple dining areas, and HUGE entertaining area with pool table, games, TV's and bar. Private bedrooms and large bunk-bed room that sleeps four. Perfect for large groups or your next celebration. Stay for a weekend or a week with Hermann Trolley service available.

LocationAir conditioningOutdoor spaces

5.0 out of 5 average rating, 34 reviews

Top guest favorite

A serene landscape is captured at sunrise, featuring a lone tree silhouetted against a vibrant sky. Rolling hills stretch into the distance, bathed in warm morning light, while a frosted ground adds a touch of winter's chill.

Vacation home in Norwood

Janie Holler Hide-a-way

Come stay at the ranch! As we no longer need a farmhand, we are offering the cabin as a place to relax and enjoy the Ozarks at their finest! Come enjoy stunning views, sunrises and sunsets, fresh country air, starlit skies, and of course, cows. All from your porch. The house has been recently repainted, a soaking tub added, and the gas fireplace upgraded. The kitchen is fully furnished and a propane grill provided. Park your vehicle in the shop beside the house. Live the simple life!

LocationFamilyWifi

5.0 out of 5 average rating, 118 reviews

Guest favorite

Vacation home in Branson

Indoor Pool/Hot Tub/Lake-Pointe Royale Resort Fun!

Easy walk in with just a couple of steps from the parking lot in front of the door. Beautifully decorated 2BR/2BA condo in Branson’s gated Pointe Royale community! Enjoy indoor/outdoor pools, tennis, fitness center, and golf just steps away. Lake Taneycomo is within walking distance—perfect for fly fishing from the private park. Close to Branson shows, theaters, dining, and shopping. Dog-friendly (up to 2 with approval). The perfect Branson getaway for families, couples, and anglers alike!

FamilyValueParking

4.94 out of 5 average rating, 100 reviews

Top guest favorite

A covered porch features a blend of comfortable seating arrangements and a glass-top table. Lush greenery surrounds the space, complemented by potted plants on the walls. The area is well-lit by natural light filtering through the overhead panels, creating a welcoming outdoor atmosphere.

Vacation home in Forest Park South East

Lovely, updated 2-bedroom apartment in The Grove

Centrally located and spacious 2nd floor apartment with private off-street parking. Updated kitchen with 2nd floor porch with bistro table. Includes Keurig coffee maker and all the basics you will need. Stackable washer/dryer. Bedroom 1 has queen bed with high thread count linens. Bedroom 2 has full bed and lots of natural light. A walk-in closet/office space. Family room is warm & inviting with Roku TV. Beautiful shared patio and fenced in backyard. Enjoy all that St. Louis has to offer!

LocationValueHospitality

4.97 out of 5 average rating, 187 reviews

Top guest favorite

A vibrant game room is showcased, featuring a dark sectional sofa adorned with colorful pillows. A mural of a French Bulldog wearing sunglasses is displayed on the orange and blue wall. Vintage arcade games and a shiny air hockey table are visible in the background.

Vacation home in Branson West

Reunion-Ready! Sleeps 40- Near Silver Dollar City

The Complete Reunion Setup | Sleeps Up to 40 Perfect for large, multigenerational gatherings, this duplex in StoneBridge Resort offers nearly 7,000 sq ft designed for organized, stress-free group stays. With two full homes under one booking, your family can stay together while spreading out across multiple living areas, kitchens, porches, and entertainment spaces. Just 5 minutes from Silver Dollar City and near Table Rock Lake, enjoy both convenience and a peaceful resort setting.

FamilyLocationCheck-in

5.0 out of 5 average rating, 16 reviews

Top guest favorite

Vacation home in Hollister

Lakeview,HotTub,Firepit,Pools,Branson,BigCedar

Enjoy lake views and quick access to Branson, Big Cedar, Silver Dollar City, golf, ThunderRidge and more. This modern yet cozy 4BR/4BA sleeps 14 and features a private hot tub, fireplace, firepit, 55"/65" TVs in every room, 1G Wi-Fi, coffee bar, 2 washer/dryer sets, and a large covered deck with a TV, grill, and stunning views of Table Rock Lake and the Ozarks. Indoor and outdoor (seasonal) pools included. Modern yet cozy, I strive to offer more than just the basics!

LocationFamilyView

4.98 out of 5 average rating, 85 reviews

Top guest favorite

A cozy living area is visible with comfortable seating options arranged around a central coffee table. Light beige walls complement a blue and white rug, while large windows draped with sheer curtains allow natural light to filter in. A bedroom can be seen through an open door.

Vacation home in Reeds Spring

Top Notch Retreat 1 Mile from Silver Dollar City!

Have an unforgettable Branson getaway at our spacious 2-bedroom, 2-bathroom vacation rental that comfortably sleeps 6. Located in a peaceful and private community on a private drive only minutes from Silver Dollar City. You can relax on the patio that overlooks the Ozarks, fish in the private lake, take a hike down one of the nature trails or go swimming in one of the two pools. Whatever you decide to do, we're sure you'll have a great time at our vacation home!

ValueFamilyGrill

4.93 out of 5 average rating, 183 reviews

Top guest favorite

The exterior of the multi-level house is visible, featuring multiple decks and black railings. Sturdy stairs lead to the upper levels, and an earthy landscape surrounds the structure, highlighting a blend of natural elements and modern design.

Vacation home in Osage Beach

Lakefront (4BR/2BA), Hot Tub, Calm cove & dock

Come make lake memories at our oasis located in one of the most coveted no wake coves at the Lake! After a restful night on king mattresses, enjoy your cup of coffee on 1 of 2 brand new decks. Swim away the day on the large dock. Enjoy close proximity by land or water to Redheads, Shorty Pants, Margaritaville, The Oaks golf course, Driftwood spa, and others! Kitchen and grill area are fully equipped.

LocationFamilyOutdoor spaces

4.94 out of 5 average rating, 67 reviews