
Guesthouse vacation rentals in Los Santos Province
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Top-rated guesthouse rentals in Los Santos Province
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A Remote Paradise in nature - Ocean View
'Tres-Palmas' sea and nature at its best! A remote hideaway on the Pacific Coast of Panama, but yet close enough to nearby towns and entertainment, Tres Palmas is the perfect place for an invigorating holiday. It is more than just a place to stay, we offer our guests personalized attention through fully equipped facilities and services for your comfort and well being. We enjoy getting to know our guests, sharing life stories and greeting you with an authentic smile for an unforgettable stay.

Cozy & quiet cabin in Cañas
It is a cozy one-bedroom unit, with a closet, a bathroom with separated toilet area, a porch and a rancho. Nestled amidst the serene hills of Canas, the property offers a tranquil retreat with a picturesque ocean view. Wake up to the enchanting melodies of howler monkeys and local birds, immersing yourself in the beauty of nature every morning. While the cabana doesn’t have its own kitchenette, fret not! You’ll have access to a nearby fully equipped community kitchen, shared between 2-3 people.

Grateful Casita
Take it easy at this calm and tranquil getaway after a day of surfing or night of dancing. This is a spacious casita on a property with a larger occupied home. The outside spaces are shared, including the pool. The casita has a small kitchenette, outdoor shower, loft with a double bed and the best view in Venao. No parties or other guests allowed. This is your retreat away from town in a gated community. You need a vehicle to stay here. It is a 10 minute drive from the gas station in Venao.

Alma Residencia - Jungle & 5 minute walk to beach
Alma Residencia is a calm & comfortable retreat for surfers, artists, and nature lovers. Nestled between jungle mountains and the ocean, our space offers a simple, peaceful base to rest, create, & explore Cambutal. WiFi, A/C, & the convenience of Pizzería Madera (Jan - May) located on-site. Spend your days surfing, hiking, or spotting wildlife, and your evenings stargazing under clear skies. A warm, natural escape—just minutes from the beach and surrounded by the beauty of the jungle.

Ginger House/House for a violinist
Relax in this unique and peaceful getaway in a private neighborhood. Just a 5-minute walk to the beach, from the house you can hear the water of the creek and the birds singing in the trees, allowing you to enjoy the nature and tranquility of the surroundings. The accommodation features a large terrace with a barbecue area, an outdoor bathroom and shower, and a deck overlooking the creek. Ideal for nature lovers, remote work, surfing, yoga, meditation, hiking, and fishing.

Tiger Beach Cottage + Detached Room @ The Divers
A relaxing getaway for a whole group or family right across the beach. Located at Los Buzos Resort and its world famous fishing & adventure lodge where guests have direct access to the many activities and amenities it has to offer like its 400 acre private nature reserve Parque Los Buzos where guests can experience the lush Panamanian wilderness and wildlife on more than 40k of trails. Los Buzos has many thrilling activities waiting. We live where the adventure is.

Accommodation in Las Tablas
Enjoy the simplicity of this quiet and centrally located accommodation. Just a 10-minute walk from downtown Las Tablas, the birthplace of Panamanian culture and folklore with its activities and festivities. It offers basic services for short stays. The owner can provide information to the guest to visit nearby beaches and indicate means of transportation to visit nearby districts such as Pedasí and activities of interest in the province.

Country House with Pool in La Enea de Guararé
Far from the capital city, come and enjoy Panamanian folklore in a rustic but cozy space, living an indigenous experience. Relax in the pool or rest in a hammock, breathe fresh air, near the sea, surrounded by spacious and natural gardens for a good walk. Close to the Port of Guararé where you can enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian skirts.

PUNTA CAÑAS
The Cabañas de Isla Cañas are 2 rooms designed so you can enjoy the relaxation in the middle of nature that you deserve so much. We love that you feel at home, that's why we have equipped one of our cabins with a basic kitchen that has a refrigerator, stove and kitchen utensils, you can also make BBQ, you have hammocks so you can enjoy your stay with your family, we are located just a 7-minute walk from Isla Cañas Beach.

La Casita del Abuelo
This private place with full private bathroom is perfect for solo adventurers or a couple, seeking peace and relaxation in an authentic environment near the beach and town. This cute hideaway is located minutes’ walks from town and bus stop and about two miles from the nearest beach. It is a new, very clean, private, secure place, and it includes private use of an adjacent bohio with hammocks, barbecue grill, and bar.

"La Jungla" Cabaña close to the beach
New room with shared kitchen and private bathroom close to the beach. You can enjoy all that Cambutal has to offer from this place. It has easy access so you dont need 4x4. Its located 500m from the beach, or 5 mins walking. The room has its own little green area and a large bathroom in the back. We try yo be close to nature and have a cool community here. We are happy to welcome new comers and old faces to Cambutal :)

Casita Verde 411
Ocean View Jungle Casita • 500 m from 411 Surf Spot • Off-Grid Retreat 🌊🌴 Wake up to waves and tropical birds in our cozy Casita, just a 3-min walk from the famous 411 Surf Spot. Between lush rainforest and the Pacific, this off-grid retreat offers adventure and relaxation. Why You’ll Love It Here: Surf in the morning, relax in the hammock by day, and stargaze at night – far from crowds, surrounded by nature.
Popular amenities for Los Santos Province guesthouse rentals
Family-friendly guest house rentals

Country House with Pool in La Enea de Guararé

Tiger Beach Cottage + Detached Room @ The Divers

Bedroom, kitchen, bathroom and terrace

A Remote Paradise in nature - Ocean View

Independent Room in La Villa Los Santos

"La Jungla" Cabaña close to the beach

Ginger House/House for a violinist

PUNTA CAÑAS
Guest house rentals with a patio

Casa Pesca

Catch & Relax Cottage @ The Divers

Catch & Relax Cottage + Detached Room @ Los Buzos

Las Tablas House Alquiler

Casa Pesca

Fourth Studio/Festivities

Tiger Beach Cottage @ The Divers

Casa Pesca
Other guesthouse vacation rentals

Catch & Relax Cottage + Detached Room @ Los Buzos

Country House with Pool in La Enea de Guararé

Tiger Beach Cottage + Detached Room @ The Divers

Bedroom, kitchen, bathroom and terrace

A Remote Paradise in nature - Ocean View

Independent Room in La Villa Los Santos

"La Jungla" Cabaña close to the beach

Ginger House/House for a violinist
Destinations to explore
- Rentals with an accessible height bed Los Santos Province
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- Family-friendly rentals Los Santos Province
- Rentals with a patio Los Santos Province
- Rentals with a fire pit Los Santos Province
- Rentals with pools Los Santos Province
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- Guesthouse rentals Panama
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