Santee vacation rentals

Book unique vacation rentals, houses, and more on Airbnb

Top-rated vacation rentals in Santee

Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.

0 of 0 items showing

1 of 3 pages

Guest favorite

Guesthouse in El Cajon

4.99 out of 5 average rating, 151 reviews

Modern mountain guest house. Incredible views

Neighboring San Diego, quaint country living with incredible views minutes from everything, breathtaking sunsets, 20 mins to beach, close by hiking trails, and only 3 minutes hop on the freeway. Full Kitchen, Laundry, and Living area and with beautiful furnishings, a perfect home away from home. Whether traveling for work or play we have had guests stay for a conference in San Diego or just to visit friends and hit the beach a few days, we look forward to you loving our home as much as we do.

Nov 11 – 18

$154 per night

Guest favorite

Guest suite in Santee

4.95 out of 5 average rating, 251 reviews

Spacious 1 bedroom unit w/ king bed & parking

Come relax in this bright & spacious 1 bedroom detached unit with private entrance. This room has a king bed, full bathroom, table & chairs, mini fridge/freezer, microwave, closet w/ hangers, dresser, Tv and beautiful mountain views. La Jolla Beaches, downtown San Diego, the Zoo, and Sea World are 25 minutes away. Santee Lakes is just a short drive away where you can enjoy fishing, paddle boating, splash park, biking and picnic area. Mission Gorge Trails is also located just 5 minutes away.

Jun 9 – 16

$72 per night

Guest favorite

Guesthouse in La Mesa

4.92 out of 5 average rating, 205 reviews

Fig Tree Bungalow

Enjoy your stay in San Diego in this newly renovated guesthouse. Centrally located about a mile from Hwy 8, Hwy 125, and the Grossmont Trolley Station & Transit Center. Only a 15-20 minute drive to downtown, the airport, the beaches, and most of San Diego's other popular tourist attractions. This cozy, two-story, detached unit is located behind my home, and has its own private entrance and partitioned yard for your enjoyment. There's plenty of street parking directly in front of the house.

Sep 16 – 23

$107 per night

Guest favorite

Home in Alpine

4.99 out of 5 average rating, 142 reviews

Fully Fenced Alpine Property with Guest House

Our guest house is located in the back of our personal property & kept private by fencing. Our property is fully fenced & guests have access in & out by using a keypad. We have laundry facilities, a queen size bed in the master bedroom, a sofa sleeper in the living room/kitchen area and a private patio with bbq. We occupy the main home on the property. We have 2 dogs on the property so other animals are not recommended at this location. Children play equipment is not included with Airbnb.

Oct 3 – 10

$95 per night

Guest favorite

Home in La Mesa

4.85 out of 5 average rating, 176 reviews

Newer "Manor Studio"

Centrally located in San Diego County this brand new studio style unit has a private entrance, private patio area and street parking. Furnished with a queen size bed, love seat, full bathroom and kitchen area. One large drawer to accommodate personal items, and a wall rack to hang clothing. There is a smart TV with WiFi streaming capabilities and lots of USB plugs to charge your devices. On street parking in front of unit (no parking in driveway). No Pets allowed. No Hair Dying allowed.

Oct 5 – 12

$97 per night

Guest favorite

Guesthouse in La Mesa

4.97 out of 5 average rating, 168 reviews

Cozy Coop with a View

This house is perfect for a private get away. There is a patio bar & a large picture frame window that commands the best views in the area. Sit & enjoy the large patio right off the entryway to the house. I have been told our home used to be a chicken coop in the 50-60's. It is far different now, we just finished a complete remodel. Everything is updated, upgraded & ready for you. Being on the top of the hill you get the nice views, but sounds carries as well, please respect the neighbors.

Oct 1 – 8

$121 per night

Guest favorite

Home in La Mesa

4.93 out of 5 average rating, 177 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

Jan 12 – 19

$124 per night

Guest favorite

Home in La Mesa

4.99 out of 5 average rating, 120 reviews

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

Jul 5 – 12

$113 per night

Guest favorite

Barn in La Mesa

4.95 out of 5 average rating, 315 reviews

Enchanting Barn San Diego/La Mesa

DESCRIPTION: Relax and Enjoy the converted barn that is safe, cozy, and private. The unit has it's own private entrance secured with a Keyless entry lock. Inside is a Cal King therapy foam bed, TV, Blu-ray player, Bluetooth/CD stereo, and additional USB connection. Extra space has a large desk area. The unit has a private bathroom that includes a walk in shower. Freshly washed towels & linens are provided. *we have a pet goat that would love to meet you! Dedicated 5g Internet access

Oct 4 – 11

$92 per night

Guest favorite

Guesthouse in El Cajon

4.98 out of 5 average rating, 190 reviews

Fletcher Hills - modern 1 BR.Easy, no step access.

** 48 hours between check-ins. Thorough cleaning and sanitizing.. Four night minimum stay. Dogs ONLY are welcomed on a case by case basis. They must be house trained and are not permitted on any furniture. If you instant book, you must contact me about your pet within 24 hours. Smoking is permitted in the outside areas - patio, gazebo, yard. Easy freeway access helps any commute to downtown and area attractions. Having your own vehicle is the best way to get around..

Apr 3 – 10

$102 per night

Guest favorite

Guesthouse in La Mesa

4.99 out of 5 average rating, 132 reviews

Stunning Guest House 15 min. from Zoo, Downtown

Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego and 18 minutes to a beach. Unique private property with mid-century and one-of-a kind furniture in a comfortable living space. Enjoy IPAs on your private deck or coffee in bright Fiesta cups, watch TV while leaning back in the handcrafted Nicaraguan rocker or the 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed. Like eclectic? This place exudes it.

Sep 1 – 8

$138 per night

Guest favorite

Apartment in La Mesa

4.97 out of 5 average rating, 139 reviews

Mt. Helix apartment with panoramic views

Mt. Helix apartment with great views from private balcony located centrally in La Mesa on quiet street. Apartment is on 2nd floor of private home on an acre lot. PLEASE NOTE: Apartment is on 2nd floor and an outside staircase is required to enter the apartment. 1 parking space is designated in driveway. Quiet Hours are 10:00pm - 7:00am. No smoking/vaping anywhere on the property.

Aug 3 – 10

$94 per night

Vacation rentals for every style

Get the amount of space that is right for you

Popular amenities for Santee vacation rentals

Gym

BBQ grill

Laptop-friendly workspace

Wifi

Air conditioning

Stay near Santee's top sights

Santee Trolley Square23 locals recommend

Walmart13 locals recommend

Carlton Oaks Country Club3 locals recommend

Santee Drive In Theatre7 locals recommend

Greek Chicken3 locals recommend

Olive Garden Italian Restaurant16 locals recommend

Other great vacation rentals in Santee

Guest favorite

Guest suite in La Mesa

4.91 out of 5 average rating, 108 reviews

Stylish Boho Studio | Walk to Cafes | Outdoor Living

Nov 17 – 24

$133 per night

Guest favorite

Guesthouse in La Mesa

4.97 out of 5 average rating, 117 reviews

San Diego Newly Built Private Guesthouse (Sleep 5)

Dec 14 – 21

$124 per night

Guest favorite

Guest suite in San Diego

4.97 out of 5 average rating, 149 reviews

Guesthouse near SDSU in Upscale Area - Cal King

Sep 26 – Oct 3

$92 per night

Guest favorite

Home in Lakeside

5.0 out of 5 average rating, 30 reviews

Terra Mesa - Charming Retreat

Jan 1 – 8

$86 per night

Guest favorite

Home in El Cajon

4.98 out of 5 average rating, 88 reviews

Suite Charles Way: A Cozy Fletcher Hills Studio

Oct 10 – 17

$97 per night

Guest favorite

Guest suite in Lakeside

5.0 out of 5 average rating, 74 reviews

Cozy, secure, and quiet studio in Lakeside

Apr 10 – 17

$97 per night

Guest favorite

Guesthouse in El Cajon

4.93 out of 5 average rating, 54 reviews

Hilltop Casita Mount Helix

Jul 14 – 21

$85 per night

Superhost

Home in El Cajon

4.93 out of 5 average rating, 29 reviews

Lovely Unique Retro house with beautiful yard

Nov 3 – 10

$112 per night

Show all

Other great vacation rentals in Santee

Guest favorite

Home in Lakeside

5.0 out of 5 average rating, 12 reviews

The Morey de Prieto Surf Ranch

Sep 22 – 29

$136 per night

Superhost

Home in El Cajon

5.0 out of 5 average rating, 7 reviews

Cozy 1BR Home with Lovely Front Yard

Dec 20 – 27

$113 per night

Guest favorite

Guest suite in La Mesa

5.0 out of 5 average rating, 35 reviews

Emerald King Wellness Suite w/ Sauna & Workspace

Sep 2 – 9

$122 per night

Guest favorite

Guest suite in Lakeside

5.0 out of 5 average rating, 54 reviews

Hillside Retreat with Views

Dec 1 – 8

$141 per night

Guest favorite

Tiny home in La Mesa

5.0 out of 5 average rating, 97 reviews

Casita de Pueblo - Private Yard, La Mesa Village

Nov 26 – Dec 3

$113 per night

Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 48 reviews

ino Mt. Helix

Aug 28 – Sep 4

$115 per night

Guest favorite

Guesthouse in La Mesa

5.0 out of 5 average rating, 61 reviews

Private 1 BR Paradise retreat

Dec 13 – 20

$114 per night

Guest favorite

Bungalow in El Cajon

4.84 out of 5 average rating, 74 reviews

Stylish Relaxation-Panoramic Views-Private OASIS!

May 1 – 8

$107 per night

Show all

Quick stats about vacation rentals in Santee

Total rentals
100 properties
Rentals with dedicated workspaces
50 properties have a dedicated workspace
Rentals with a pool
40 properties have a pool
Pet-friendly rentals
20 properties allow pets
Family-friendly rentals
40 properties are a good fit for families
Total number of reviews
2.3K reviews

Frequently Asked Questions

Are there house rentals with a dedicated workspace in Santee?
Yes! Work meets play with ease at over 20 house rentals in Santee featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there Santee house rentals on Airbnb with pools?
Yes! Dive into the perfect getaway at one of over 20 house rentals with pools in Santee, available on Airbnb. Make a splash and soak up the sun in style!
How much does it cost to stay in private suite rentals in Santee?
Experience the best of Santee with our private suite rentals, starting at about $50 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do condo rentals in Santee have air conditioning?
Absolutely! We offer over 10 condo rentals with air conditioning in Santee. Enjoy a tailored experience with all the comforts you desire.
Are there pet-friendly house rentals in Santee?
Four-legged friends are welcome in Santee. Choose from more than 10 house rentals for guests traveling with pets.
Are there family-friendly house rentals in Santee?
Santee has more than 20 family-friendly house rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Do private suite rentals in Santee have wifi?
Absolutely! We offer over 10 private suite rentals with wifi in Santee. Enjoy a tailored experience with all the comforts you desire.
What are the most popular amenities for Condo Rentals in Santee?
Enhance your stay in our Condo Rentals with the most popular amenities: over 10 homes with wifi, over 10 homes with air conditioning, and more. Indulge in the ultimate retreat, tailored to your preferences.

Santee vacation rentals

Top-rated vacation rentals in Santee

Vacation rentals for every style

Houses

Hotels

Unique stays

Popular amenities for Santee vacation rentals

Stay near Santee's top sights

Other great vacation rentals in Santee

Guest suite in La Mesa

Guesthouse in La Mesa

Guest suite in San Diego

Home in Lakeside

Home in El Cajon

Guest suite in Lakeside

Guesthouse in El Cajon

Home in El Cajon

Other great vacation rentals in Santee

Home in Lakeside

Home in El Cajon

Guest suite in La Mesa

Guest suite in Lakeside

Tiny home in La Mesa

Guesthouse in La Mesa

Guesthouse in La Mesa

Bungalow in El Cajon

Quick stats about vacation rentals in Santee

Total rentals

Rentals with dedicated workspaces

Rentals with a pool

Pet-friendly rentals

Family-friendly rentals

Total number of reviews

Frequently Asked Questions

Are there house rentals with a dedicated workspace in Santee?

Are there Santee house rentals on Airbnb with pools?

How much does it cost to stay in private suite rentals in Santee?

Do condo rentals in Santee have air conditioning?

Are there pet-friendly house rentals in Santee?

Are there family-friendly house rentals in Santee?

Do private suite rentals in Santee have wifi?

What are the most popular amenities for Condo Rentals in Santee?

Destinations to explore